Results 151 to 160 of about 182,132 (342)

DNA‑Directed Assembly of Photonic Nanomaterials for Diagnostic and Therapeutic Applications

Advanced Materials, EarlyView.
DNA‐directed assembly offers a powerful strategy for constructing structured photonic nanomaterials with precise spatial control. This review provides a comprehensive overview of recent advancements in DNA‐assembled photonic nanomaterials for diagnostics and therapeutics, highlighting key design principles, functionalization strategies, and optical ...
Longjiang Ding, Bing Liu, Andreas Peil, Sisi Fan, Jie Chao, Na Liu   +5 more
wiley   +1 more source

MTR4 drives liver tumorigenesis by promoting cancer metabolic switch through alternative splicing. [PDF]

, 2020
The metabolic switch from oxidative phosphorylation to glycolysis is required for tumorigenesis in order to provide cancer cells with energy and substrates of biosynthesis.
Chen, Wancheng, Dou, Wenlong, Feng, Bingbing, Fu, Xuemei, He, Yang-Fan, Ji, Kai-Yuan, Jiang, Lei, Kim, Jinchul, Li, Qingjiao, Mai, Taoyi, Tang, Qingshuang, Xiang, Le-Yang, XU, Yang, Yang, Dinghua, Ying, Yue, Yu, Lili, Zhou, Jianlong   +16 more
core   +1 more source

Profiling of RNAs from Human Islet-Derived Exosomes in a Model of Type 1 Diabetes [PDF]

, 2019
Type 1 diabetes (T1D) is characterized by the immune-mediated destruction of insulin-producing islet β cells. Biomarkers capable of identifying T1D risk and dissecting disease-related heterogeneity represent an unmet clinical need.
Evans-Molina, Carmella, G. Mirmira, Raghavendra, Jiyun Kang, Nicole, Krishnan, Preethi, Syed, Farooq   +4 more
core   +1 more source

Targeting exosomes enveloped EBV‐miR‐BART1‐5p‐antagomiRs for NPC therapy through both anti‐vasculogenic mimicry and anti‐angiogenesis

, 2023
Jianguo Wang, Yan Liu, Yuanbin Zhang, Xiaoyang Li, Min Fang, Dong Qian   +5 more
openalex   +1 more source

Inclusion Biogenesis, Methods of Isolation and Clinical Application of Human Cellular Exosomes [PDF]

, 2020
Max Tschuschke, Ievgeniia Kocherova, Artur Bryja, Paul Mozdziak, Ana Angelova Volponi, Krzysztof Janowicz, Rafał Sibiak, Hanna Piotrowska‐Kempisty, Dariusz Iżycki, Dorota Bukowska, Paweł Antosik, Jamil Awad Shibli, Marta Dyszkiewicz-Konwińska, Bartosz Kempisty   +13 more
openalex   +1 more source

Harnessing Photo‐Energy Conversion in Nanomaterials for Precision Theranostics

Advanced Materials, EarlyView.
Harnessing photo‐energy conversion in nanomaterials enables precision theranostics through light‐driven mechanisms such as photoluminescence, photothermal, photoelectric, photoacoustic, photo‐triggered surface‐enhanced Raman scattering (SERS), and photodynamic processes. This review explores six fundamental principles of photo‐energy conversion, recent
Jingyu Shi, Yadi Fan, Qin Zhang, Yingying Huang, Mo Yang   +4 more
wiley   +1 more source

Tumor-homing exosomes enable targeted delivery of siRNA and isoimperatorin for overcoming BTK inhibitor resistance in DLBCL

Materials Today Bio
Diffuse large B-cell lymphoma (DLBCL) is the most common type of lymphoma, but over one-third of patients relapse or develop refractory disease after first-line therapy. Novel therapeutic strategies are required to address persistent unmet clinical needs
Ruowen Sun, Yanchao Yang, Bin Zhang, Jiayuan Chen, Ye Wang, Zehui Jiang, Linlin Zhang, Milad Ashrafizadeh, Gautam Sethi, Jing Shen, Zuofei Chi   +10 more
doaj   +1 more source

Downregulation of exosomal miR-192-5p and miR-204-5p in subjects with nonclassic apparent mineralocorticoid excess

Journal of Translational Medicine, 2019
Background The “nonclassic” apparent mineralocorticoid excess (NC-AME) has been identified in approximately 7% of general population. This phenotype is characterized by low plasma renin activity (PRA), high serum cortisol (F) to cortisone (E) ratio, low ...
Alejandra Tapia-Castillo, Dominic Guanzon, Carlos Palma, Andrew Lai, Eric Barros, Fidel Allende, Andrea Vecchiola, Carlos E. Fardella, Carlos Salomón, Cristian A. Carvajal   +9 more
doaj   +1 more source

Writing a wrong: Coupled RNA polymerase II transcription and RNA quality control [PDF]

, 2019
Processing and maturation of precursor RNA species is coupled to RNA polymerase II transcription. Co-transcriptional RNA processing helps to ensure efficient and proper capping, splicing, and 3' end processing of different RNA species to help ensure ...
Hughes, Katlyn D., Mosley, Amber L., Peck, Sarah A., Victorino, Jose F.   +3 more
core   +1 more source

Engineered Plasmonic and Fluorescent Nanomaterials for Biosensing, Motion, Imaging, and Therapeutic Applications

Advanced Materials, EarlyView.
A schematic illustration of how noble metals can be used to create nanoparticles (NPs) or nanoclusters (NCs). Noble metal NPs, due to their plasmonic properties, enable photothermal therapy and surface‐enhanced Raman scattering (SERS). In contrast, NCs, which lack a plasmonic resonance band, exhibit fluorescence, making them ideal for bioimaging ...
David Esporrín‐Ubieto, Juan C. Fraire, Daniel Sánchez‐deAlcázar, Samuel Sánchez   +3 more
wiley   +1 more source