A prospective adaptive utility trial to validate performance of a novel urine exosome gene expression assay to predict high-grade prostate cancer in patients with prostate-specific antigen 2-10ng/ml at initial biopsy [PDF]
, 2018 BACKGROUND: Discriminating indolent from clinically significant prostate cancer (PCa) in the initial biopsy setting remains an important issue. Prospectively evaluated diagnostic assays are necessary to ensure efficacy and clinical adoption.
Andriole, Gerry +12 more
core +1 more source
Circulating Pro-Inflammatory Exosomes Worsen Stroke Outcomes in Aging [PDF]
, 2021 Hongxia Zhang +6 more
openalex +1 more source
Advanced Materials Technologies, EarlyView.A technique for precise patterning of highly biocompatible, low‐viscosity bioinks, such as fibrin, is crucial for recapitulating the physical organization of tissues. In this study, a configurable 3D‐printed microstructured stamp with micropillars is used to control the spatial arrangement of low‐viscosity bioinks and to assess cellular interactions ...
Yejin Choi, Soo Jee Kim, Je‐Kyun Park
wiley +1 more source
Stabilization of Exosome-targeting Peptides via Engineered Glycosylation [PDF]
, 2015 Michelle Hung, Joshua N. Leonard
openalex +1 more source
Advancing Clinical Medicine with Raman Spectroscopy: Current Trends and Future Perspectives
Advanced Photonics Research, EarlyView.Raman spectroscopy and microscopy may become excellent tools in clinical medicine, including hematology, oncology, infectious diseases, neurology, gastroenterology, reproductive medicine, rheumatology, and cardiovascular research. However, many challenges such as signal interference, standardization issues, and limited clinical application need to be ...
Jiří Bufka +5 more
wiley +1 more source
Advanced Science, EarlyView.Steroid receptor coactivator‐1 (SRC‐1) reprograms tumor‐associated macrophages (TAMs) via signal transducer and activator of transcription 1(STAT1)‐mediated matrix metallopeptidase 12 (MMP12) transcription to drive perineural invasion (PNI) in pancreatic cancer.
Ke Cheng +9 more
wiley +1 more source
MicroRNA-631 deriving from bone marrow mesenchymal stem cell exosomes facilitates the malignant behavior of non-small cell lung cancer via modulating the E2F family of transcription factor 2/phosphatidylinositol 3‐kinase/Akt signaling pathway [PDF]
, 2022 Hong Lv +6 more
openalex +1 more source
Advanced Science, EarlyView.The S100A4/STAT3 axis promotes Rmrp transcription in AEC‐IIs and Rmrp expression in AEC‐II‐derived exosomes. Upon entry into AMs, Rmrp binds to and blocks the ubiquitination and degradation of ZFP36. Increased ZFP36 induced Pfkfb3 mRNA decay by binding to AREs in the 3′ UTR, curbing glycolysis and immune responses of AMs and aggravating SII and ...
Chengxi Liu +17 more
wiley +1 more source
Fibronectin on extracellular vesicles from microvascular endothelial cells is involved in the vesicle uptake into oligodendrocyte precursor cells. [PDF]
, 2019 学位記番号 ...
Osawa, Sho +2 more
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