Results 191 to 200 of about 83,398 (334)

Molecular and cellular paradigms of multidrug resistance in cancer

Cancer Reports, Volume 5, Issue 12, December 2022., 2022
Abstract Background The acquisition of resistance to chemotherapy is a major hurdle in the successful application of cancer therapy. Several anticancer approaches, including chemotherapies, radiotherapy, surgery and targeted therapies are being employed for the treatment of cancer.
Foram U. Vaidya, Abu Sufiyan Chhipa, Vinita Mishra, Vishal Kumar Gupta, Shiv Govind Rawat, Ajay Kumar, Chandramani Pathak   +6 more
wiley   +1 more source

Potential upscaling protocol establishment and wound healing bioactivity screening of exosomes isolated from canine adipose-derived mesenchymal stem cells. [PDF]

Sci Rep
Pamulang YV, Oontawee S, Rodprasert W, Padeta I, Sa-Ard-Lam N, Mahanonda R, Osathanon T, Somparn P, Pisitkun T, Torsahakul C, Sawangmake C.   +10 more
europepmc   +1 more source

The Trojan exosome hypothesis

, 2003
Stephen J. Gould, Amy M. Booth, James E. K. Hildreth   +2 more
openalex   +1 more source

Mast cell- and dendritic cell-derived exosomes display a specific lipid composition and an unusual membrane organization [PDF]

, 2004
Karine Laulagnier, Claude Motta, Safouane M. Hamdi, Sébastien Roy, Florence Fauvelle, Jean‐François Pageaux, Toshihide Kobayashi, Jean‐Pierre Salles, Bertrand Perret, Christian Bonnerot, Michel Record   +10 more
openalex   +1 more source

Novel Electroactive Therapeutic Platforms for Cardiac Arrhythmia Management

Advanced Science, EarlyView.
Electroactive platforms offer promising applications in cardiac arrhythmia. Based on their energy sources and mechanisms, electroactive platforms are categorized into i) direct electrical stimulation, ii) self‐powered electroactive systems, iii) physical stimuli‐mediated electroactive systems, and iv) conductive systems, and their applications in ...
Juwei Yang, Longfei Li, Yiran Hu, Zhou Li, Wei Hua   +4 more
wiley   +1 more source

Genome-wide screening and validation of exosome-derived TLN1 as a regulator of epithelial-mesenchymal transition in lung cancer. [PDF]

Sci Rep
Ruan X, Wan X, Ma W, Liu J, Tian T, Zhang J, Zhi J, Qiu M, Zhao M, Wang Q, Li P.   +10 more
europepmc   +1 more source

Degradation of AP2 During Reticulocyte Maturation Enhances Binding of Hsc70 and Alix to a Common Site on TfR for Sorting into Exosomes [PDF]

, 2004
Charles Géminard, Aude De Gassart, Lionel Blanc, Michel Vidal   +3 more
openalex   +1 more source

Locoregional Immune Checkpoint Blockade and Remodeling of Lymph Nodes by Engineered Dendritic Cell‐Derived Exosomes for Suppressing Tumor Progression and Metastasis

Advanced Science, EarlyView.
The study develops engineered exosomes (EmDEX@GA) for locoregional immunomodulation of tumor‐draining lymph node (TDLN). EmDEX@GA can actively target to TDLN and remodel its immunosuppressive microenvironment through the synergistic effects of PD‐1/PD‐L1 blockade and STING pathway activation, subsequently enhance anti‐tumor immunity and suppress tumor ...
Yizhen Wang, Xiaomin Guo, Jingya Qin, Yifan Xue, Peng Zhang, Yadong Liu, Moyang Chen, Guanghao Zhu, Xinqiu Song, Lili Cheng, Bo Liu, Jie Liu, Jie Ren   +12 more
wiley   +1 more source

Mast Cell-Derived Exosomes Induce Phenotypic and Functional Maturation of Dendritic Cells and Elicit Specific Immune Responses In Vivo

, 2003
Dimitris Skokos, Hany Goubran Botros, Christian E. Demeure, Joëlle Morin, Roger Péronet, Gerd Birkenmeier, Sarah Boudaly, Salaheddine Mécheri   +7 more
openalex   +1 more source

Engineering Extracellular Vesicles Derived from 3D Cultivation of BMSCs Enriched with HGF Ameliorate Sepsis‐Induced Lung Epithelial Barrier Damage

Advanced Science, EarlyView.
3D culture of MSCs upregulates gene expression of matrix metalloproteinases (MMPs), growth factors (GFs), and increases the production of extracellular vesicles (EVs). Proteomic analysis reveals 642 upregulated proteins in 3D‐EVs, including HGF. These 3D‐EVs, enriched with HGF, protect lung epithelial cells from apoptosis and barrier damage in septic ...
Yong Chen, Feihong Lin, Tong Zhang, Zhuoran Xiao, Yuanli Chen, Dongsheng Hua, Yu Wang, Juan Wei, Tian Jin, Xin Lv   +9 more
wiley   +1 more source