Results 201 to 210 of about 84,164 (334)

Optimization of Lipid Nanoparticles with Robust Efficiency for the Delivery of Protein Therapeutics to Augment Cancer Immunotherapy

Advanced Science, EarlyView.
This study develops lipid nanoparticles (LNPs) combining cationic and ionizable lipids for efficient cytosolic protein delivery. Optimized LNPs deliver functional proteins, including antibodies, enzymes, and Cas9, with high serum stability and albumin‐mediated endocytosis.
Lanfang Ren, Zeda Zhao, Yuqing Chao, Panting Yu, Zhoufang Mei, Bing Du, Yiyun Cheng   +6 more
wiley   +1 more source

Lymphatic metastasis in non‐small cell lung cancer: recent discoveries and novel therapeutic targets

, 2022
Cancer Communications, Volume 42, Issue 12, Page 1403-1406, December 2022.
Xiayao Diao, Chao Guo, Shanqing Li
wiley   +1 more source

Mast Cell-Derived Exosomes Induce Phenotypic and Functional Maturation of Dendritic Cells and Elicit Specific Immune Responses In Vivo

, 2003
Dimitris Skokos, Hany Goubran Botros, Christian E. Demeure, Joëlle Morin, Roger Péronet, Gerd Birkenmeier, Sarah Boudaly, Salaheddine Mécheri   +7 more
openalex   +1 more source

Prospects for urinary proteomics: Exosomes as a source of urinary biomarkers (Review Article) [PDF]

, 2005
Ewout J. Hoorn, Trairak Pisitkun, Robert Zietse, Peter Groß, JOERGEN FROKIAER, Nam Sun Wang, Patricia A. Gonzales, Robert A. Star, Mark A. Knepper   +8 more
openalex   +1 more source

Harnessing exosomes for targeted drug delivery systems to combat brain cancer. [PDF]

Cancer Cell Int
Basyoni AE, Atta A, Salem MM, Mohamed TM.   +3 more
europepmc   +1 more source

The INAVA mRNA in Extracellular Vesicles Activates Normal Ovarian Fibroblasts by Phosphorylation–Ubiquitylation Crosstalk of HMGA2

Advanced Science, EarlyView.
Ovarian cancer‐derived extracellular vesicles (EVs) transfer INAVA mRNA to normal ovarian fibroblasts (NOFs). Translated INAVA protein inhibits HMGA2 phosphorylation‐dependent ubiquitylation and proteasomal degradation, promoting NOF activation.
Lingkai Gu, Zhangjin Shen, Shizhen Shen, Conghui Wang, Yuwan Liu, Xinyi Wei, Mengxia Zheng, Jiaxin Gu, Xiaojing Chen, Yi Sun, Junfen Xu, Yan Lu, Weiguo Lu   +12 more
wiley   +1 more source

Presentation of donor major histocompatibility complex antigens by bone marrow dendritic cell-derived exosomes modulates allograft rejection1

, 2003
Hélène Pêche, Michèle Heslan, Claire Usal, Sebastián Amigorena, María Cristina Cuturi   +4 more
openalex   +1 more source

Heat Shock Protein 70 Surface-Positive Tumor Exosomes Stimulate Migratory and Cytolytic Activity of Natural Killer Cells [PDF]

, 2005
Robert Gastpar, Mathias Gehrmann, María A. Bausero, Alexzander Asea, Catharina C. Groß, Josef Schroeder, Gabriele Multhoff   +6 more
openalex   +1 more source

Humanized Saccharomyces cerevisiae provides a facile and effective tool to identify damaging human variants that cause exosomopathies. [PDF]

G3 (Bethesda)
Ahammed KS, Fasken MB, Corbett AH, van Hoof A.   +3 more
europepmc   +1 more source

Engineered Stem Cell Clusters for Extracellular Vesicles‐Mediated Gene Delivery to Rejuvenate Chondrocytes and Facilitate Chondrogenesis in Osteoarthritis Therapy

Advanced Science, EarlyView.
BMSCmotif+miR874/MS system is designed as a gene delivery platform utilizing engineered bone marrow mesenchymal stem cell (BMSC)‐derived extracellular vesicles (EVs) for intercellular communication to achieve sustained delivery of miRNA‐874‐3p. Rejuvenation of chondrocytes and promotion of chondrogenesis are achieved by inhibition of the NF‐κB pathway,
Yuezhou Wu, Yubo Feng, Fei Hu, Xu Zheng, Yurun Ding, Xuesong Liu, Shicheng Huo, Zhuocheng Lyu   +7 more
wiley   +1 more source