Results 311 to 320 of about 182,132 (342)

Metabolism‐Regulating Nanomedicines for Cancer Therapy

Advanced NanoBiomed Research, EarlyView.
This review highlights metabolism‐regulating nanomedicines designed to target glycolytic, lipid, amino acid, and nucleotide pathways in tumors. By incorporating metabolism‐regulating agents into versatile nanocarriers such as liposomes, micelles, dendrimers, and engineered bacteria, these platforms achieve targeted delivery, controlled release ...
Xiao Wu, Shiyi Geng, Jian Yang
wiley   +1 more source

Exosome-based modulation of ferroptosis in neurological disorders: mechanisms, therapeutic potential, and translational challenges. [PDF]

Front Immunol
Bao X, Chen L, Yu H, Xie Y, Luo L, Luo L, Wang H, Chen R, Cheng Y, Sun D, Zhang C.   +10 more
europepmc   +1 more source

Nanobiotechnology‐Based Approaches for Targeted Glioma Therapy

Advanced NanoBiomed Research, EarlyView.
Nanoparticle systems cross the blood–brain barrier to deliver drugs precisely to glioma cells. Lipid, polymeric, and magnetic carriers enable controlled release, tumor targeting, and microenvironment modulation. These nanoplatforms enhance chemotherapy, radiotherapy, and immunotherapy, improving therapeutic efficacy while reducing systemic toxicity ...
Jinwei Li, Yibo He, Yang Zhang, Lining Arnold Ju, Yao Wang, Jianxuan Zhou, Yinying Chai, Xuhui Hui, ShiYuan Tong, Si Zhang, Yanli Tan, Yinyan Wang   +11 more
wiley   +1 more source

RNA Degradation in Pluripotent Stem Cells: Mechanisms, Crosstalk, and Fate Regulation. [PDF]

Cells
Jeong S, Oh M, Han J, Kim SK.
europepmc   +1 more source

Multifunctional Hydrogel‐Based wound Dressings for Scar‐Free Healing: Design Principles, Therapeutic Mechanisms, and Clinical Translation Challenges

Advanced NanoBiomed Research, EarlyView.
This review integrates scar biology with hydrogel‐based therapeutic strategies, offering a phase‐specific framework to correlate hydrogel functions with scar‐influencing events. It highlights innovations such as stimuli‐responsive hydrogels, nanocomposite systems, and 3D‐printed scaffolds, while addressing clinical translation challenges like ...
Haonan Chai, Zhenxing Wang, Jingyi Ju, Jiaming Sun   +3 more
wiley   +1 more source

Dual-ligand engineered exosome regulates WNT signaling activation to promote liver repair and regeneration. [PDF]

Nat Commun
Yang L, Wang S, Qiao Z, Liu Y, Wang X, Liu L, Yang C, Ding J, Lei M, Zheng J, Hu W, Chen YG, Chan YS.   +12 more
europepmc   +1 more source

In vitro evaluation of 3D-printed conductive chitosan–polyaniline scaffolds with exosome release for enhanced angiogenesis and cardiomyocyte protection

Amir Hashemi, Masoumeh Ezati, Inna Zumberg, Larisa Chmelíková, Zdenka Fohlerová, Valentýna Provazník   +5 more
openalex   +2 more sources

Chicken Pulmonary MicroRNAs Targeting the PB2 (Segment 1) of Avian Influenza Virus

Animal Research and One Health, EarlyView.
The PB2 segment of H5N1 is essential for replication and host adaptation. We screened 200 miRNAs and identified five (gga‐miR‐17‐3p, gga‐miR‐29a‐5p, gga‐miR‐1718, gga‐miR‐16c‐5p, and gga‐miR‐1744‐5p) using thermodynamic stability of heteroduplex, seed sequence complementarity, conservation, and accessibility, offering insights into host antiviral ...
Akanksha Choudhary, Nidhishree N. S, Rakesh Kumar Pundir, Muhasin Asaf V. N, Anamika Mishra, Ashwin Ashok Raut, Megha Agarwal, Amod Kumar   +7 more
wiley   +1 more source

Exosome-Based Therapeutics: A Natural Solution to Overcoming the Blood-Brain Barrier in Neurodegenerative Diseases. [PDF]

MedComm (2020)
Sun M, Qin F, Bu Q, Zhao Y, Yang X, Zhang D, Cen X.   +6 more
europepmc   +1 more source

5‐Methylcytosine Analysis of miRNAs in Minimal Change Disease

Biotechnology and Applied Biochemistry, EarlyView.
ABSTRACT Minimal change disease (MCD) is a glomerular disorder, which is the most common cause of nephrotic syndrome in children. Additionally, the prevalence of MCD in adults has been increasing in recent years. During protein synthesis, noncoding RNAs can be regulated through a variety of modifications, which helps preserve biological diversity and ...
Huiyi Zeng, Dandan Li, Yunyi Li, Chen Yun, Xinzhou Zhang, Wenyu Gong, Mengyun Xiao, Haitao Li, Zhipeng Zeng, Ruqi Tan, Yishen Yang, Shaodong Luan, Yong Dai, Lianghong Yin, Donge Tang   +14 more
wiley   +1 more source