Results 91 to 100 of about 62,378 (298)

Selective pharmacological inhibition alters human carcinoma lung cell-derived extracellular vesicle formation

open access: yesHeliyon, 2023
Exosomes also termed small extracellular vesicles (sEVs) are important mediators of intercellular communication in many physiological and pathological processes such as protein clearance, immunity, infections, signaling, and cancer.
Ayodeji O. Ipinmoroti   +4 more
doaj  

KSRP-PMR1-exosome association determines parathyroid hormone mRNA levels and stability in transfected cells

open access: yesBMC Cell Biology, 2009
Background Parathyroid hormone (PTH) gene expression is regulated post-transcriptionally through the binding of the trans-acting proteins AU rich binding factor 1 (AUF1), Upstream of N-ras (Unr) and KH-type splicing regulatory protein (KSRP) to an AU ...
Schoenberg Daniel R   +6 more
doaj   +1 more source

The Effect of Galactose on the Expression of Genes Regulated by Rrp6p [PDF]

open access: yes, 2017
Gene expression is a multi-faceted phenomenon, governed not only by the sequence of nucleotides, but also by the extent to which a particular gene gets transcribed, how the transcript is processed, and whether or not the transcript ever makes it out of ...
Callahan, Kevin, Pelkowski, Mary Megan
core   +1 more source

Structure of the RBM7-ZCCHC8 core of the NEXT complex reveals connections to splicing factors

open access: yes, 2016
The eukaryotic RNA exosome participates extensively in RNA processing and degradation. In human cells, three accessory factors (RBM7, ZCCHC8 and hMTR4) interact to form the nuclear exosome targeting (NEXT) complex, which directs a subset of non-coding ...
Benda, C.   +6 more
core   +1 more source

Nanocarrier‐Based Targeting of Pattern Recognition Receptors as an Innovative Strategy for Enhancing Sepsis Therapy

open access: yesAdvanced Healthcare Materials, EarlyView.
This review highlights recent progress in nanocarriers targeting pattern recognition receptors (PRRs), including Toll‐like and NOD‐like receptors, for enhancing the treatment of bacterial sepsis and related complications. These nanomedicines deliver antibiotics and anti‐inflammatory agents while modulating immune responses.
Eman A. Ismail   +3 more
wiley   +1 more source

A new landscape of host–protozoa interactions involving the extracellular vesicles world [PDF]

open access: yes, 2018
This version is free to view and download for private research and study only. Not for re-distribution, re-sale or use in derivative works. © Cambridge University Press 2018Extracellular vesicles (EVs) are released by a wide number of cells including ...
Bruno Gavinho   +11 more
core   +2 more sources

PLUS: Primary Layer for Universal Sensing Enabling Improved Immunocapture of Biomarkers in Clinical Scenarios

open access: yesAdvanced Healthcare Materials, EarlyView.
Primary Layer for Universal Sensing (PLUS), a universal coating for bioprobe immobilization across diverse substrates, is introduced. Unlike conventional methods, PLUS is directly grown from dopamine and avidin, creating a roughened surface with abundant biotin‐binding sites.
Nayoung Son   +5 more
wiley   +1 more source

Exosome-mediated Transfer of αvβ3 Integrin from Tumorigenic to Nontumorigenic Cells Promotes a Migratory Phenotype. [PDF]

open access: yes, 2016
The αvβ3 integrin is known to be highly upregulated during cancer progression and promotes a migratory and metastatic phenotype in many types of tumors.
Fedele, Carmine   +5 more
core   +2 more sources

Molecular Mechanisms of Extracellular Vesicle Biogenesis and Their Impact on the Design of Custom EVs

open access: yesAdvanced Healthcare Materials, EarlyView.
Extracellular vesicles (EVs) are pivotal mediators of intercellular communication and disease, yet the fundamental mechanisms controlling their biogenesis and cargo selection remain unclear. This limitation hinders their diagnostic utility and therapeutic development.
Luís Carvalho Ferraz   +2 more
wiley   +1 more source

RNA-regulatory exosome complex suppresses an apoptotic program to confer erythroid progenitor cell survival in vivo. [PDF]

open access: yesBlood Adv, 2023
Fraga de Andrade I   +5 more
europepmc   +1 more source

Home - About - Disclaimer - Privacy