Results 101 to 110 of about 62,378 (298)

Exosomal αvβ6 integrin is required for monocyte M2 polarization in prostate cancer [PDF]

, 2018
Therapeutic approaches aimed at curing prostate cancer are only partially successful given the occurrence of highly metastatic resistant phenotypes that frequently develop in response to therapies.
Altieri, Dario C., Bowler, Nicholas, Craig Hooper, D., Dutta, Anindita, Ertel, Adam, Fedele, Carmine, Forsberg, Flemming, Fortina, Paolo, Gabrilovich, Dmitry I., Harshyne, Larry A., Kean, Rhonda B., Kelly, William K., Kossenkov, Andrew V., Krishn, Shiv Ram, Kurtoglu, Senem, Languino, Lucia R., Liu, Qin, Lu, Huimin, Speicher, David W., Stanczak, Maria, Tang, Hsin-Yao, Wang, Kerith, Weinreb, Paul H., Yu, Lei   +23 more
core   +1 more source

Engineering a Human‐Sized Common Bile Duct Prototype with Regenerative Potential: In Vitro Evaluation of Mechanics, Function, Degradation, and Immune Modulation

Advanced Healthcare Materials, EarlyView.
This study presents a multiphasic bile duct construct composed of biocompatible materials and cells, featuring an inner layer that supports biliary epithelium growth, a middle layer providing mechanical strength, and an outer cell‐permissive layer designed to support future in vivo integration.
Mattia Pasqua, Marianna Barbuto, Matteo Calligaris, Roberto Di Gesù, Duilio Pagano, Rosalia Busà, Salvatore Gruttadauria, Simone Dario Scilabra, Antonio D'Amore, Maria Giovanna Francipane   +9 more
wiley   +1 more source

RNA-regulatory exosome complex confers cellular survival to promote erythropoiesis. [PDF]

Nucleic Acids Res, 2021
Mehta C, Fraga de Andrade I, Matson DR, Dewey CN, Bresnick EH.   +4 more
europepmc   +1 more source

Exosomes are natural carriers of exogenous siRNA to human cells in vitro [PDF]

, 2013
© 2013 Shtam et al. Background: Exosomes are nano-sized vesicles of endocytic origin that are involved in cell-to-cell communication including shuttle RNA, mainly mRNA and microRNA.
Filatov, MV, Kil, YV, Kovalev, RA, Makarov, EM, Shtam, TA, Varfolomeeva, EY   +5 more
core   +1 more source

Advanced Nanoparticle Therapeutics for Targeting Neutrophils in Inflammatory Diseases

Advanced Healthcare Materials, EarlyView.
This review highlights recent advances in nanoparticle‐based strategies to modulate neutrophil activity in inflammatory diseases. By targeting inflammatory neutrophils, NET formation, and neutrophil apoptosis or recruitment, these approaches aim to improve therapeutic precision.
Min Ji Byun, Elizabeth S. Nakasone, Ha Eun Shin, Hyojin Lee, Jong‐Chan Park, Wonhwa Lee, Wooram Park, Chun Gwon Park, Juwon Park, Se‐Na Kim   +9 more
wiley   +1 more source

RNA substrate length as an indicator of exosome interactions in vivo [version 1; referees: 2 approved, 1 approved with reservations]

Wellcome Open Research, 2017
Background: The exosome complex plays key roles in RNA processing and degradation in Eukaryotes and Archaea. Outstanding structural studies identified multiple pathways for RNA substrates into the exosome in vitro, but identifying the pathway followed by
Clémentine Delan-Forino, Claudia Schneider, David Tollervey   +2 more
doaj   +1 more source

Autoantibodies directed to novel components of the PM/Scl complex, the human exosome [PDF]

, 2001
Rick Brouwer, Wilma TM Vree Egberts, G.J.D. Hengstman, Reinout Raijmakers, Baziel G.M. van Engelen, H. P. Seelig, Manfred Renz, Rudolf Mierau, E. Genth, Ger J.M. Pruijn, Walther J. van Venrooij   +10 more
openalex   +1 more source

Current perspectives on the role of TRAMP in nuclear RNA surveillance and quality control [PDF]

, 2015
The TRAMP complex assists the nuclear exosome to degrade a broad range of ribonucleic acid (RNA) substrates by increasing both exoribonucleolytic activity and substrate specificity.
Huang, Z, Lee, JTH, Pan, K, Wong, CM
core   +1 more source

From Mechanoelectric Conversion to Tissue Regeneration: Translational Progress in Piezoelectric Materials

Advanced Materials, EarlyView.
This review highlights recent progress in piezoelectric materials for regenerative medicine, emphasizing their ability to convert mechanical stimuli into bioelectric signals that promote tissue repair. Key discussions cover the intrinsic piezoelectric properties of biological tissues, co‐stimulation cellular mechanisms for tissue regeneration, and ...
Xinyu Wang, Sílvio Terra Stefanello, Victor Shahin, Yun Qian   +3 more
wiley   +1 more source

RNA substrate length as an indicator of exosome interactions in vivo [version 2; referees: 3 approved]

Wellcome Open Research, 2017
Background: The exosome complex plays key roles in RNA processing and degradation in Eukaryotes and Archaea. Outstanding structural studies identified multiple pathways for RNA substrates into the exosome in vitro, but identifying the pathway followed by
Clémentine Delan-Forino, Claudia Schneider, David Tollervey   +2 more
doaj   +1 more source