Results 131 to 140 of about 315,886 (312)
Advancements in Programmable Lipid Nanoparticles: Exploring the Four-Domain Model for Targeted Drug Delivery [PDF]
arXivProgrammable lipid nanoparticles, or LNPs, represent a breakthrough in the realm of targeted drug delivery, offering precise spatiotemporal control essential for the treatment of complex diseases such as cancer and genetic disorders. In order to provide a more modular perspective and a more balanced analysis of the mechanism, this review presents a ...
arxiv
Recent Advancements in Lung Cancer Metastasis Prevention Based on Nanostrategies
Advanced Science, EarlyView.Metastasis is the leading cause of death in patients with lung cancer. Nanomedicine can be used to prepare efficient drug delivery systems owing to their advantages and plays an important role in the synergistic antimetastasis of lung cancer. This comprehensive review summarizes the emerging nanostrategies against lung cancer metastasis based on the ...
Fan Xu +7 more
wiley +1 more source
arXiv, 2013 We introduce decomposition complexes of posets, which generalize order complexes. The main advantage of our construction is that decomposition complexes are closed under taking products. Other special instances of this theory include nested set complexes as well as Bergman complexes.
arxiv
Decay of mRNAs targeted by RISC requires XRN1, the Ski complex, and the exosome [PDF]
, 2005 Tamás I. Orbán, Elisa Izaurralde
openalex +1 more source
Advanced Science, EarlyView.Injectable pH responsive conductive hydrogel for intelligent delivery of metformin and exosomes to alleviate myocardial ischemia‐reperfusion injury. The hydrogel responds to the weakly acidic microenvironment of ischemic injury and can significantly reduce the production of intracellular ROS and enhance cardiac conduction, thereby resisting apoptosis ...
Nianlan Cheng +11 more
wiley +1 more source
Advances in exosome biomarkers for cervical cancer
Cancer Medicine, Volume 11, Issue 24, Page 4966-4978, December 2022., 2022 Cancer‐derived exosomes may promote CC metastasis by boosting cellular epithelial‐mesenchymal transformation (EMT), controlling the proliferation, invasion, or migration of cancer cells, as well as influencing immune escape and aiding angiogenesis.
Zihan Ran +5 more
wiley +1 more source
Theranostics aspect of extracellular vesicle in cancer liquid biopsy
The Journal of Liquid BiopsyRecent advances in cancer treatment emphasize the pivotal role of extracellular vesicles (EVs), especially exosomes (a subpopulation of EVs, originating from endosomes). Exosomes are signaling molecules in the cellular system.
Shivani Ravipati +6 more
doaj
Correction: Circulating, soluble forms of major histocompatability complex antigens are not exosome‐associated [PDF]
, 2006 Philippa A. MacKay +6 more
openalex +1 more source
NETs‐CD44‐IL‐17A Feedback Loop Drives Th17‐Mediated Inflammation in Behçet's Uveitis
Advanced Science, EarlyView.In experimental autoimmune uveitis (EAU), neutrophils interact with T helper 17 (Th17) cells through neutrophil extracellular traps (NETs) to exert a pro‐inflammatory effect. In vitro and in vivo experiments identify that NETs promote IL‐17A secretion in Th17 cells via CD44, and increasing IL‐17A further induces more NETs formation.
Yi Wu +11 more
wiley +1 more source
Exosomes and their roles in the chemoresistance of pancreatic cancer
Cancer Medicine, Volume 11, Issue 24, Page 4979-4988, December 2022., 2022 Despite the development of multiple promising chemotherapeutic agents as recommended first‐line treatment for PC, the therapeutic efficacy is largely limited by unwanted drug resistance.Exploring the relation between exosomes and chemoresistance may be conducive to understanding molecular mechanisms and taking effective measures to reduce the ...
Yubin Pan +4 more
wiley +1 more source