Results 181 to 190 of about 315,886 (312)

Cryo-EM Structure of Substrate-Engaged Nuclear Exosome Targeting (Next) Complex

, 2020
M Rhyan Puno, Christopher D. Lima
openalex   +1 more source

Microenvironmental Modulation for Therapeutic Efficacy of Extracellular Vesicles

Advanced Science, EarlyView.
Recent studies highlighted the heterogeneity of EVs and the influence of microenvironmental signals on their therapeutic efficacy. This review offers a comprehensive overview of strategies and mechanisms to optimize the therapeutic efficacy of EVs through physical, biochemical, and mechanical modulation.
Bilu Xiang, Shiying Zhang, Irene Shuping Zhao, Xueqi Gan, Yang Zhang   +4 more
wiley   +1 more source

Recent Advances in Enhancing the Sensitivity of Biosensors Based on Field Effect Transistors

Advanced Electronic Materials, EarlyView.
This paper discusses the methods to enhancing the detection sensitivity of biosensors in three aspects: overcoming the influence of Debye shielding effects, promoting the binding efficiency of analytes and transistor surface, and improving the structures of device.
Yuying Zhou, Tongshi Feng, Yao Li, Xiang Ao, Shengfa Liang, Xiaonan Yang, Lingfei Wang, Xiaoxin Xu, Wenchang Zhang   +8 more
wiley   +1 more source

Additional file 4 of CRABP1-complexes in exosome secretion

Supplementary Material 4. Name: Additional File 4_Supplementary Fig. 1. File format: .pdf. Title: Supplementary Fig. 1. Flow cytometry analyses of exosomes collected from supernatant of P19 cells. Description: Cells were pretreated with DMSO or 1 µM AGN193109 for 1 h.
Nhieu, Jennifer, Wei, Chin-Wen, Ludwig, Megan, Drake, Justin M., Wei, Li-Na   +4 more
openaire   +1 more source

Integrating Aggregate Materials and Machine Learning Algorithms: Advancing Detection of Pathogen‐Derived Extracellular Vesicles

Aggregate, EarlyView.
Pathogen‐derived extracellular vesicle detection: theoretical insights and advanced methodologies: This review explores the theoretical foundations and practical applications of pEV detection, emphasizing the challenges and innovative strategies involving novel aggregate materials and machine learning for enhanced diagnostic accuracy.
Lihan Lai, Yun Su, Cong Hu, Zehong Peng, Wei Xue, Liang Dong, Tony Y. Hu   +6 more
wiley   +1 more source

Exosome complex genes mediate RNA degradation and predict survival in mantle cell lymphoma. [PDF]

Oncol Lett, 2019
Zhang W, Zhu J, He X, Liu X, Li J, Li W, Yang P, Wang J, Hu K, Zhang X, Li X, Jing H.   +11 more
europepmc   +1 more source

Additional file 3 of CRABP1-complexes in exosome secretion

Supplementary Material 3. Name: Additional File 3_Supplementary Table 3. File format: .pdf. Title: Supplementary Table 3. List of primers for quantitative RT-PCR. Description: Primer sequences for gene markers used in gene expression qPCR experiments.
Nhieu, Jennifer, Wei, Chin-Wen, Ludwig, Megan, Drake, Justin M., Wei, Li-Na   +4 more
openaire   +1 more source

Phototherapy via Modulation of β‐Amyloid in Combating Alzheimer's Disease

Aggregate, EarlyView.
This review introduces the light‐regulated Aβ aggregation, highlighting four applications: photodynamic therapy (PDT), photothermal therapy (PTT), photopharmacology, and photobiomodulation (PBM) systems. It also summarizes the current issues and proposes the prospects of photo‐induced modulation of Aβ aggregation and clearance as a therapeutic strategy
Yunhua Zhang, Chengyuan Qian, Yuncong Chen, Weijiang He, Zijian Guo   +4 more
wiley   +1 more source

Structure and reconstitution of yeast Mpp6-nuclear exosome complexes reveals that Mpp6 stimulates RNA decay and recruits the Mtr4 helicase

, 2017
Elizabeth V. Wasmuth, John C. Zinder, Dimitrios Zattas, Mom Das, Christopher D. Lima   +4 more
openalex   +1 more source

Development and Application of Organic Sonosensitizers in Cancer Therapy

Aggregate, EarlyView.
This review provides a comprehensive overview of organic sonosensitizers employed in cancer treatment, describing their underlying mechanisms and structure‐activity relationship in terms of sonodynamic therapy. The significance of nanotechnology and combination therapy with other oncological modalities (photothermal therapy, photodynamic therapy, etc.)
Yuhan Ding, Yuchen Yang, Omer Aras, Feifei An, Mengjiao Zhou, Yichao Chai   +5 more
wiley   +1 more source