Results 191 to 200 of about 315,886 (312)
Retinal regions shape human and murine Müller cell proteome profile and functionality
Main Points We defined Müller cells heterogeneity in the macular and peripheral human retina. Signaling pathways shaping this glial heterogeneity include proteins important for interaction with vesicular secretion, extracellular matrix and cell adhesion.
Lew Kaplan+15 more
wiley +1 more source
Multifunctional Ultra‐Bright Plasmonic Gold@Fluorescence Nanoprobe for Biomedical Applications
Plasmonic gold nanoparticles (AuNPs) with intrinsic superiorities in metal‐enhanced fluorescence (MEF) have been widely utilized in amplifying signal enhancement, fluorescent labeling, and theranostics. This review systematically discusses plasmonic AuNPs‐driven MEFs, from their enhancement mechanisms, influencing factors, and enhanced types, to their ...
Caiping Ding+4 more
wiley +1 more source
Macrophage‐derived MLKL in alcohol‐associated liver disease: Regulation of phagocytosis
EtOH causes leaky gut allowing bacteria and PAMPs into the liver, resulting in hepatic inflammation and injury. We demonstrate that LPS induces STAT1‐mediated expression and phosphorylation of MLKL in macrophages and identify a novel function that myeloid MLKL translocates to phagosomes and lysosomes and regulates phagocytosis, which contributes to the
Xiaoqin Wu+16 more
wiley +1 more source
Abstract Background Intracerebral hemorrhage (ICH) remains a devastating neurological disorder with limited therapeutic options. Neural stem cell (NSC)‐based therapies have emerged as a potential regenerative approach, yet the molecular mechanisms regulating NSC behavior require further elucidation.
Wei Dai+7 more
wiley +1 more source
Exosome complex components 1 and 2 are vital for early mammalian development. [PDF]
Srinivasan S, He X, Mirza S, Mager J.
europepmc +1 more source
Poly(A) Tail-dependent Exonuclease AtRrp41p fromArabidopsis thaliana Rescues 5.8 S rRNA Processing and mRNA Decay Defects of the Yeast ski6 Mutant and Is Found in an Exosome-sized Complex in Plant and Yeast Cells [PDF]
Julia A. Chekanova+3 more
openalex +1 more source
Structural studies of the human Nuclear EXosome Targeting complex [PDF]
Sofos, Nicholas Egholm+2 more
openaire +3 more sources
Cancer cell membrane‐based nanoparticles (CCM‐NPs) and cancer cell‐derived small extracellular vesicles (CsEVs) are emerging as promising drug delivery systems for targeted cancer treatment. Advances in nanotechnology have paved the way for innovative drug delivery systems that enhance the effectiveness of cancer treatment.
Wei Zhang+4 more
wiley +1 more source