Results 191 to 200 of about 315,886 (312)

Retinal regions shape human and murine Müller cell proteome profile and functionality

open access: yesGlia, Volume 71, Issue 2, Page 391-414, February 2023., 2023
Main Points We defined Müller cells heterogeneity in the macular and peripheral human retina. Signaling pathways shaping this glial heterogeneity include proteins important for interaction with vesicular secretion, extracellular matrix and cell adhesion.
Lew Kaplan   +15 more
wiley   +1 more source

Adaptor protein CD2AP and L-type lectin LMAN2 regulate exosome cargo protein trafficking through the Golgi complex.

open access: green, 2017
Sang‐Ho Kwon   +4 more
openalex   +1 more source

Multifunctional Ultra‐Bright Plasmonic Gold@Fluorescence Nanoprobe for Biomedical Applications

open access: yesAggregate, EarlyView.
Plasmonic gold nanoparticles (AuNPs) with intrinsic superiorities in metal‐enhanced fluorescence (MEF) have been widely utilized in amplifying signal enhancement, fluorescent labeling, and theranostics. This review systematically discusses plasmonic AuNPs‐driven MEFs, from their enhancement mechanisms, influencing factors, and enhanced types, to their ...
Caiping Ding   +4 more
wiley   +1 more source

Macrophage‐derived MLKL in alcohol‐associated liver disease: Regulation of phagocytosis

open access: yesHepatology, EarlyView., 2022
EtOH causes leaky gut allowing bacteria and PAMPs into the liver, resulting in hepatic inflammation and injury. We demonstrate that LPS induces STAT1‐mediated expression and phosphorylation of MLKL in macrophages and identify a novel function that myeloid MLKL translocates to phagosomes and lysosomes and regulates phagocytosis, which contributes to the
Xiaoqin Wu   +16 more
wiley   +1 more source

Transplanting neural stem cells overexpressing miRNA‐21 can promote neural recovery after cerebral hemorrhage through the SOX2/LIN28‐let‐7 signaling pathway

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Abstract Background Intracerebral hemorrhage (ICH) remains a devastating neurological disorder with limited therapeutic options. Neural stem cell (NSC)‐based therapies have emerged as a potential regenerative approach, yet the molecular mechanisms regulating NSC behavior require further elucidation.
Wei Dai   +7 more
wiley   +1 more source

Structural studies of the human Nuclear EXosome Targeting complex [PDF]

open access: yesActa Crystallographica Section A Foundations and Advances, 2015
Sofos, Nicholas Egholm   +2 more
openaire   +3 more sources

Recent Advances in Cancer Cell Membrane‐Based Nanoparticles and Cancer Cell‐Derived Small Extracellular Vesicles as Drug Delivery Platforms

open access: yesAdvanced NanoBiomed Research, EarlyView.
Cancer cell membrane‐based nanoparticles (CCM‐NPs) and cancer cell‐derived small extracellular vesicles (CsEVs) are emerging as promising drug delivery systems for targeted cancer treatment. Advances in nanotechnology have paved the way for innovative drug delivery systems that enhance the effectiveness of cancer treatment.
Wei Zhang   +4 more
wiley   +1 more source

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