Results 241 to 250 of about 315,886 (312)

Exosomes in human semen restrict HIV-1 transmission by vaginal cells and block intravaginal replication of LP-BM5 murine AIDS virus complex

, 2015
Marisa Nia Madison, Philip H. Jones, Chioma M. Okeoma   +2 more
openalex   +1 more source

Engineered brain‐targeting exosome for reprogramming immunosuppressive microenvironment of glioblastoma

Exploration, EarlyView.
An acid‐cleavable Tf‐modified engineering exosome‐based brain‐targeting delivery system (ACTE) was proposed using metabolic glycoengineering and bioorthogonal click chemistry, enabling co‐delivery of siTGF‐β and DOX for GBM treatment. ACTE was featured by higher BBB transcytosis efficiency and hierarchical targeting delivery to GBM cells.
Jun Yang, Yong Li, Shaoping Jiang, Yuxin Tian, Mengjie Zhang, Shuai Guo, Pengfei Wu, Jianan Li, Lin Xu, Wenpei Li, Yushu Wang, Huile Gao, Yuanyu Huang, Yuhua Weng, Shaobo Ruan   +14 more
wiley   +1 more source

Harnessing the Potential of Exosomes in Therapeutic Interventions for Brain Disorders. [PDF]

Int J Mol Sci
Bai L, Yu L, Ran M, Zhong X, Sun M, Xu M, Wang Y, Yan X, Lee RJ, Tang Y, Xie J.   +10 more
europepmc   +1 more source

Understanding the complex role of exosomes in intestinal ischemia-reperfusion injury: from pathogenesis to protection

Qin Ye, Zihang Yu, Liang Nie, Feixiang Wang, Guo Mu, Bin Lu   +5 more
openalex   +1 more source

Synthetic Biology‐Based Engineering Cells for Drug Delivery

Exploration, EarlyView.
Synthetic biology‐based therapeutic cells for drug delivery: Engineered cells effectively transport and release drugs through their intelligence and controllability, such as feedback pathways and external stimuli (e.g., light and ultrasound). The integration of nanotechnology, including nanoparticles, biofilms, and artificial cells, enhances ...
Wenzhe Yi, Shuangshuang Hu, Xindi Qian, Wenlu Yan, Yaping Li   +4 more
wiley   +1 more source

Exosome isolation and characterization for advanced diagnostic and therapeutic applications. [PDF]

Mater Today Bio
Mukerjee N, Bhattacharya A, Maitra S, Kaur M, Ganesan S, Mishra S, Ashraf A, Rizwan M, Kesari KK, Tabish TA, Thorat ND.   +10 more
europepmc   +1 more source

Odontogenic exosomes simulating the developmental microenvironment promote complete regeneration of pulp-dentin complex in vivo

Yifan Wang, Jing Mao, Yujie Wang, Rui Wang, Nan Jiang, Xiaohan Hu, Xin Shi   +6 more
openalex   +1 more source

Engineered Exosome‐Based Senolytic Therapy Alleviates Stroke by Targeting p21+CD86+ Microglia

Exploration, EarlyView.
We identified a harmful immune cell type, p21+CD86+ microglia, driving post‐stroke inflammation and developed a targeted exosome‐based therapy (Que@micro‐Exo) to eliminate these cells. This innovative treatment reduced inflammation, alleviated brain damage, and improved recovery in stroke models, offering a promising strategy for stroke and other ...
Jialei Yang, Shipo Wu, Miao He
wiley   +1 more source

Exosomes in oral squamous cell carcinoma: functions, challenges, and potential applications. [PDF]

Front Oncol
Zhao B, Li Z, Li R.
europepmc   +1 more source

Loss of the Integrator and Nuclear Exosome Targeting complexes disrupts oogenesis and causes the emergence of atypical transcripts in Drosophila

Y.R. Lee, Adriano Biasini, Cindy Tipping, Seong Hyeon Hong, Phillip D. Zamore   +4 more
openalex   +1 more source