Results 31 to 40 of about 6,729,673 (335)

Exosome in Cardiovascular Diseases: A Complex World Full of Hope [PDF]

open access: yesCells, 2019
Exosomes are a subgroup of extracellular vesicles containing a huge number of bioactive molecules. They represent an important means of cell communication, mostly between different cell populations, with the purpose of maintaining tissue homeostasis and ...
Gloria Bellin   +7 more
semanticscholar   +5 more sources

The Pyrococcus Exosome Complex [PDF]

open access: hybridJournal of Biological Chemistry, 2005
Celso Raul Romero Ramos   +5 more
openalex   +2 more sources

A therapeutic-grade purified exosome system alleviates osteoarthritis by regulating autophagy through the BCL2–Beclin1 axis [PDF]

open access: yesJournal of Nanobiotechnology
Background Osteoarthritis is a common and progressive degenerative joint disorder marked by cartilage degradation, subchondral bone remodeling, and chondrocyte apoptosis.
Gongyin Zhao   +6 more
doaj   +2 more sources

The CCR4-NOT complex physically and functionally interacts with TRAMP and the nuclear exosome. [PDF]

open access: yesPLoS ONE, 2009
BACKGROUND:Ccr4-Not is a highly conserved multi-protein complex consisting in yeast of 9 subunits, including Not5 and the major yeast deadenylase Ccr4.
Nowel Azzouz   +3 more
doaj   +1 more source

Exosomes/MoS2 complex for targeting and effective photothermal therapy [PDF]

open access: goldJournal of Nanobiotechnology
Abstract Photothermal therapy (PTT) has been an attractive tumor treatment strategy in recent years. Two-dimensional molybdenum disulfide (MoS2)-based nanomaterials with high photothermal efficiency is a critical candidate for PTT. However, the tumor-targeting capability extremely needs to be improved for effective tumor treatment. In this work,
Liyan Wang   +10 more
openalex   +3 more sources

Exosome Release by Glucose Deprivation Is Important for the Viability of TSC-Null Cells

open access: yesCells, 2022
The control of exosome release is associated with numerous physiological and pathological activities, and that release is often indicative of health, disease, and environmental nutrient stress.
Ji-Hyun Bae, Jong Hyun Kim
doaj   +1 more source

Identification of the SNARE complex that mediates the fusion of multivesicular bodies with the plasma membrane in exosome secretion

open access: yesJournal of Extracellular Vesicles, 2023
Exosomes play crucial roles in local and distant cellular communication and are involved in various physiological and pathological processes. Tumour‐derived exosomes are pivotal to tumorigenesis, but the precise mechanisms underlying their secretion ...
Chuqi Liu   +5 more
semanticscholar   +1 more source

Nab3 facilitates the function of the TRAMP complex in RNA processing via recruitment of Rrp6 independent of Nrd1. [PDF]

open access: yesPLoS Genetics, 2015
Non-coding RNAs (ncRNAs) play critical roles in gene regulation. In eukaryotic cells, ncRNAs are processed and/or degraded by the nuclear exosome, a ribonuclease complex containing catalytic subunits Dis3 and Rrp6.
Milo B Fasken   +2 more
doaj   +1 more source

An exosome‐like complex in Sulfolobus solfataricus [PDF]

open access: yesEMBO reports, 2003
We present the first experimental evidence for the existence of an exosome‐like protein complex in Archaea. In Eukarya, the exosome is essential for many pathways of RNA processing and degradation. Co‐immunoprecipitation with antibodies directed against the previously predicted Sulfolobus solfataricus orthologue of the exosome subunit ribosomal‐RNA ...
Evguenieva-Hackenberg, E.   +4 more
openaire   +3 more sources

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