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Mutational Analysis of Exostosin 1 and 2 Genes in Multiple Osteochondroma
The Indian Journal of Pediatrics, 2015To the Editor: Multiple Osteochondroma (MO) or Multiple Exostosis is a skeletal disorder characterized by out-growth of benign cartilage-capped bone tumors arising from the metaphyses of long tubular bones or from the surface of flat bones like scapula.
K. Malini +3 more
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Abstract B21: Exostosin 1 regulates cancer cell stemness in breast cancer cells
Cancer Research, 2016Abstract Cancer stem cells (CSCs), a group of cancer cells, are associated with resistance to radiation and chemotherapy and are implicated in recurrent of cancer. Exostosin 1 (EXT1) gene is widely reported as tumor suppressor and its indispensable role in elongation of heparan sulfate (HS) can speculate probable role as tumor promotor ...
Sarala Manandhar +8 more
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Journal of the American Society of Nephrology, 2023
Fernanda Zavala Miranda +7 more
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Fernanda Zavala Miranda +7 more
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Exostosin 1- and 2-Associated Lupus-Like Membranous Nephropathy in Men
Journal of the American Society of Nephrology, 2023Kana R. Amari +2 more
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Integrative oncology: Addressing the global challenges of cancer prevention and treatment
Ca-A Cancer Journal for Clinicians, 2022Jun J Mao,, Msce +2 more
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Integration of Exostosin 1 and 2 Into a Clinical Care Pathway for Membranous Nephropathy
Journal of the American Society of Nephrology, 2022Jennifer A. Brown +5 more
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Background : Exostosin-1 is a protein that encoded by the EXT1 which is one of the two endoplasmic reticulum-resident type II transmembrane glycosyltransferase, that is involved in the chain elongation step of heparan sulfate biosynthesis. Mutations in this gene cause the type I form of multiple exostoses.
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