Results 21 to 30 of about 2,624 (190)

Glomerular Exostosin-Positivity is Associated With Disease Activity and Outcomes in Patients With Membranous Lupus Nephritis [PDF]

Kidney International Reports
Introduction: The relationship of exostosin 1 and exostosin 2 (EXT1/EXT2) expression and outcomes in membranous lupus nephritis (MLN) was controversial.
Xi Xia, Suchun Li, Zhipeng Wang, Siyang Ye, Yuting Fan, Wenxing Peng, Wenfang Chen, Fengxian Huang, Ruihan Tang, Wei Chen   +9 more
doaj   +2 more sources

The potential of exogenous specialized pro-resolving mediators in protecting against sepsis-associated lung injury: a review [PDF]

Frontiers in Pharmacology
Sepsis-associated lung injury (SALI) is a critical condition with high mortality. Current therapies are limited, necessitating novel approaches. This review highlights the potential of exogenous Specialized Pro-resolving Mediators (SPMs), including ...
Jiwei Shen, Jiwei Shen, Jiwei Shen, Huiqin Shen, Huiqin Shen, Huiqin Shen, Shujun Sun, Shujun Sun, Shujun Sun, Shiwen Fan, Shiwen Fan, Shiwen Fan, Tianhao Zhang, Tianhao Zhang, Tianhao Zhang, Guobin Song, Guobin Song, Guobin Song, Ning An, Ning An, Ning An, Xiangdong Chen, Xiangdong Chen, Xiangdong Chen, Yafen Gao, Yafen Gao, Yafen Gao   +26 more
doaj   +2 more sources

MAdLandExpression: integrating sexual reproduction into the Physcomitrium patens expression atlas. [PDF]

Plant J
SUMMARY Physcomitrium patens is a bryophyte model system particularly valuable for evolutionary developmental and comparative genomics studies. Sexual reproduction in bryophytes offers unique insights into the evolution of land plant reproduction. Unlike seed plants, bryophytes have a dominant gametophyte phase and provide significant advantages for ...
Sanchez-Vera V, Lopez-Gomez E, Metz G, Haas FB, Silva-Reiriz F, Hiltemann S, Meyberg R, Marcoux DS, Fernandez-Pozo N, Rensing SA.   +9 more
europepmc   +2 more sources

Multiple osteochondromas of the antlers and cranium in a free-ranging white-tailed deer (Odocoileus virginianus) [PDF]

, 2017
This paper reports a case of multiple osteochondromas affecting the antlers and the left zygomatic bone of a free-ranging adult white-tailed buck (Odocoileus virginianus) from Georgia, USA.
Flohr, Stefan, Gomez, Santiago, Kierdorf, Horst, Kierdorf, Uwe, Miller, Karl V.   +4 more
core   +13 more sources

WCN24-2238 EXOSTOSIN 1- AND 2- POSITIVE MEMBRANOUS NEPHROPATHY IN CHINESE PATIENTS

Kidney International Reports
Hong Cheng, Guoqin Wang, Lijun Sun, Hongrui Dong, Xiaoyi Xu, Nan Ye, Min Yang, Yanyan Wang, Wenrong Cheng, Weiyi Guo, Zhirui Zhao, Xiaoyi Zhao, Yanqiu Geng, Feng Mei   +13 more
doaj   +2 more sources

Multiple Heriditary Exostoses in a Family for Three Generation of Indian Origin with Review of Literature [PDF]

Journal of Clinical and Diagnostic Research, 2014
Multiple hereditary exostoses (MHE) are an autosomal dominant disorder, consisting of multiple cartilage capped bone tumour arising from the metaphysis of long tubular bones. Mutations are seen in Exostosin-1 and Exostosin-2 genes.
Kalyani R, Prabhakar K, Gopinath B, Sheik Naseer B, Krishnamurthy DS   +4 more
doaj   +1 more source

Exostosin-1 enhances canonical Wnt signaling activity during chondrogenic differentiation [PDF]

Osteoarthritis and Cartilage, 2019
Exostosin-1 (Ext1) encodes a glycosyltransferase required for heparan sulfate (HS) chain elongation in HS-proteoglycan biosynthesis. HS chains serve as binding partners for signaling proteins, affecting their distribution and activity. The Wnt/β-catenin pathway emerged as critical regulator of chondrogenesis.
Wang, X., Cornelis, F.MF., Lories, R.J., Monteagudo, S.   +3 more
openaire   +2 more sources

Exostosin-1 Glycosyltransferase Regulates Endoplasmic Reticulum Architecture and Dynamics [PDF]

, 2020
SUMMARYThe endoplasmic reticulum (ER) is a central eukaryotic organelle with a tubular network made of hairpin proteins linked by hydrolysis of GTP nucleotides. Among post-translational modifications initiated at the ER level, glycosylation is the most common reaction.
Despoina Kerselidou, Bushra Saeed Dohai, David R. Nelson, Sarah Daakour, Nicolas De Cock, Dae-Kyum Kim, Julien Olivet, Diana C. El Assal, Ashish Jaiswal, Deeya Saha, Charlotte Pain, Filip Matthijssens, Pierre Lemaitre, Michael Herfs, Julien Chapuis, Bart Ghesquiere, Didier Vertommen, Verena Kriechbaumer, Kèvin Knoops, Carmen Lopez-Iglesias, Marc van Zandvoort, Jean-Charles Lambert, Julien Hanson, Christophe Desmet, Marc Thiry, Kyle J. Lauersen, Marc Vidal, Pieter Van Vlierberghe, Franck Dequiedt, Kourosh Salehi-Ashtiani, Jean-Claude Twizere   +30 more
openaire   +1 more source

Mutation spectrum of EXT1 and EXT2 in the Saudi patients with hereditary multiple exostoses

Orphanet Journal of Rare Diseases, 2021
Background Hereditary Multiple Exostoses (HME), also known as Multiple Osteochondromas (MO) is a rare genetic disorder characterized by multiple benign cartilaginous bone tumors, which are caused by mutations in the genes for exostosin ...
Zayed Al-Zayed, Roua A. Al-Rijjal, Lamya Al-Ghofaili, Huda A. BinEssa, Rajeev Pant, Anwar Alrabiah, Thamer Al-Hussainan, Minjing Zou, Brian F. Meyer, Yufei Shi   +9 more
doaj   +1 more source

Familial Nephropathy and Multiple Exostoses With Exostosin-1 (EXT1) Gene Mutation [PDF]

Journal of the American Society of Nephrology, 2008
Glomerular deposition of fibrillar collagen is a characteristic finding of genetically distinct conditions, including nail-patella syndrome and collagen type III glomerulopathy. A case of familial nephropathy in which steroid-sensitive nephrotic syndrome and glomerular deposits of fibrillar collagen are associated with multiple exostoses due to ...
Ian S D, Roberts, Jonathan M, Gleadle
openaire   +2 more sources