Exome resequencing and GWAS for growth, ecophysiology, and chemical and metabolomic composition of wood of Populus trichocarpa. [PDF]
BackgroundPopulus trichocarpa is an important forest tree species for the generation of lignocellulosic ethanol. Understanding the genomic basis of biomass production and chemical composition of wood is fundamental in supporting genetic improvement ...
Davis, Mark F +10 more
core +1 more source
Heparan sulfate expression in the neural crest is essential for mouse cardiogenesis [PDF]
Impaired heparan sulfate (HS) synthesis in vertebrate development causes complex malformations due to the functional disruption of multiple HS-binding growth factors and morphogens.
Carbe, Christian +12 more
core +1 more source
Genome-wide identification of pistil-specific genes expressed during fruit set initiation in tomato (Solanum lycopersicum) [PDF]
Fruit set involves the developmental transition of an unfertilized quiescent ovary in the pistil into a fruit. While fruit set is known to involve the activation of signals (including various plant hormones) in the ovary, many biological aspects of this ...
Ariizumi Tohru +8 more
core +2 more sources
Whole genome semiconductor based sequencing of farmed European sea bass (Dicentrarchus labrax) Mediterranean genetic stocks using a DNA pooling approach [PDF]
European sea bass (Dicentrarchus labrax) is an important marine species for commercial and sport fisheries and aquaculture production. Recently, the European sea bass genome has been sequenced and assembled.
Bertolini, F +5 more
core +1 more source
The structure of EXTL3 helps to explain the different roles of bi-domain exostosins in heparan sulfate synthesis [PDF]
: Heparan sulfate is a highly modified O-linked glycan that performs diverse physiological roles in animal tissues. Though quickly modified, it is initially synthesised as a polysaccharide of alternating β-d-glucuronosyl and N-acetyl-α-d-glucosaminyl ...
Chirgadze, D. Y. +10 more
core +2 more sources
Heterogeneity of Target Antigens in Sarcoidosis-Associated Membranous Nephropathy [PDF]
Introduction: Membranous nephropathy (MN) is the most common glomerular disease associated with sarcoidosis. The target antigen M-type phospholipase A2 receptor 1 (PLA2R) has been identified in a subset of sarcoidosis-associated MN. The target antigen is
Fervenza, Fernando C. +6 more
core +1 more source
Heparanase and Syndecan-4 Are Involved in Low Molecular Weight Fucoidan-Induced Angiogenesis
Induction of angiogenesis is a potential treatment for chronic ischemia. Low molecular weight fucoidan (LMWF), the sulfated polysaccharide from brown seaweeds, has been shown to promote revascularization in a rat limb ischemia, increasing angiogenesis ...
Oualid Haddad +10 more
doaj +1 more source
Loss of pRB and p107 disrupts cartilage development and promotes enchondroma formation [PDF]
The pocket proteins pRB, p107 and p130 have established roles in regulating the cell cycle through the control of E2F activity. The pocket proteins regulate differentiation of a number of tissues in both cell cycle-dependent and -independent manners ...
Danielian, Paul S. +2 more
core +1 more source
Abstract Background Racehorses undergo profound physiological changes with training and competition, but current biomarkers inadequately capture the complex molecular dynamics of exercise. This study aimed to identify novel plasma biomarkers of training adaptation and peak load using high‐throughput proteomics.
Jowita Grzędzicka +4 more
wiley +1 more source
Structural Features of Heparan Sulfate from Multiple Osteochondromas and Chondrosarcomas
Multiple osteochondromas (MO) is a hereditary disorder associated with benign cartilaginous tumors, known to be characterized by absence or highly reduced amount of heparan sulfate (HS) in the extracellular matrix of growth plate cartilage, which alters ...
Noemi Veraldi +9 more
doaj +1 more source

