Results 71 to 80 of about 20,276 (258)

Pyroptosis in Peripheral Neuropathy: From Molecular Mechanisms to Therapeutic Targeting

CNS Neuroscience &Therapeutics, Volume 32, Issue 1, January 2026.
Pyroptosis is a key inflammatory cell death pathway in peripheral neuropathy, with opposing roles: it perpetuates neuropathic pain but can be induced to kill neuroblastoma cells. This review consolidates mechanistic understanding and therapeutic strategies, arguing for a shift from disease‐centric to target‐centric treatment approaches to improve ...
Jinhuan Wei, Mingyue Liuyuan, Zhixin Ye, Xueying Wang, Xueli Zhou, Yifan Shan, Cheng He, Chunting Zhu, Chicheng Zhou, Jingyin Bao, Yonghui Zhang, Gang Chen   +11 more
wiley   +1 more source

It’s a Small World After All: The Remarkable but Overlooked Diversity of Venomous Organisms, with Candidates Among Plants, Fungi, Protists, Bacteria, and Viruses

Toxins
Numerous organisms, including animals, plants, fungi, protists, and bacteria, rely on toxins to meet their needs. Biological toxins have been classified into three groups: poisons transferred passively without a delivery mechanism; toxungens delivered to
William K. Hayes, Eric C. K. Gren, David R. Nelsen, Aaron G. Corbit, Allen M. Cooper, Gerad A. Fox, M. Benjamin Streit   +6 more
doaj   +1 more source

Staphylococcal enterotoxin O exhibits cell cycle modulating activity

Frontiers in Microbiology, 2016
Maintenance of an intact epithelial barrier constitutes a pivotal defense mechanism against infections. Staphylococcus aureus is a versatile pathogen that produces multiple factors including exotoxins that promote tissue alteration.
Elisabeth eHodille, Elisabeth eHodille, Elisabeth eHodille, Ludmila eAlekseeva, Ludmila eAlekseeva, Nadia eBerkova, Asma eSerrier, Asma eSerrier, Cedric eBadiou, Cedric eBadiou, Benoit eGilquin, Benoit eGilquin, Virginie eBrun, Virginie eBrun, Francois eVandenesch, Francois eVandenesch, Francois eVandenesch, David eTerman, Gerard eLina, Gerard eLina, Gerard eLina   +20 more
doaj   +1 more source

Necrotizing Pneumonia Caused by PVL‐Negative Methicillin‐Susceptible Staphylococcus aureus Complicated by Refractory Pneumothorax: A Case Report

Respirology Case Reports, Volume 14, Issue 1, January 2026.
Here we report a case of PVL‐negative MSSA necrotizing pneumonia in a previously healthy man that rapidly progressed to cavitary lesions and refractory pneumothorax. Despite its improvement after clindamycin‐based therapy, the patient experienced recurrent pneumothorax and chronic respiratory failure.
Shun Endo, Tomoka Yasuda, Makoto Izumi, Kazuhiro Shimaya, Yoshikazu Tsukada   +4 more
wiley   +1 more source

Considerations and challenges of septic arthritis and osteomyelitis

Equine Veterinary Education, Volume 38, Issue 1, Page 19-25, January 2026.
Summary Septic arthritis remains a common orthopaedic condition in both human and veterinary medicine which can cause serious morbidity and pose considerable challenges for clinical management. The majority of the published clinical research in humans and veterinary species has been focused on the diagnosis, treatment, prevention and outcome of this ...
J. B. Engiles, H. L. Stewart
wiley   +1 more source

Enigmatic roles of Vibrio cholerae hemolysin/cytolysin in the bacterial pathogenesis and host-pathogen interactions

Journal of Bacteriology
Vibrio cholerae cytolysin (VCC; also known as V. cholerae hemolysin) is a β-barrel pore-forming toxin (β-PFT) secreted by the cholera pathogen V. cholerae.
Mahendra Singh, Sindhoora Puravankara, Arunika Mukhopadhaya, Kausik Chattopadhyay   +3 more
doaj   +1 more source

Insecticidal activity of culture supernatants from Bacillus thuringiensis Berliner strains against Spodoptera frugiperda Smith (Lepidoptera: Noctuidae) larvae. [PDF]

, 2018
Recentemente, proteinas inseticidas vegetativas (Vips), identificadas no sobrenadante da cultura de certas cepas de Bacillus thuringiensis (B.t.), foram capazes de controlar alguns insetos-praga economicamente importantes.
BARRETO, M. R., LOGUERCIO, L. L., PAIVA, E., VALICENTE, F. H.   +3 more
core  

Progress of Programmed Cell Death in Steroid‐Induced Osteonecrosis of the Femoral Head

Orthopaedic Surgery, Volume 18, Issue 1, Page 16-30, January 2026.
Steroid‐induced osteonecrosis of the femoral head is a severe osteoarticular condition resulting from glucocorticoid overuse, characterized by femoral head bone structure collapse and cell death, now predominant among nontraumatic femoral head necroses.
Zhi Kong, Chao Han
wiley   +1 more source

Reservoir of Bacterial Exotoxin Genes in the Environment

International Journal of Microbiology, 2010
Many bacteria produce secreted virulence factors called exotoxins. Exotoxins are often encoded by mobile genetic elements, including bacteriophage (phage). Phage can transfer genetic information to the bacteria they infect.
Veronica Casas, Joseph Magbanua, Gerico Sobrepeña, Scott T. Kelley, Stanley R. Maloy   +4 more
doaj   +1 more source

Probing Genomic Aspects of the Multi-Host Pathogen Clostridium perfringens Reveals Significant Pangenome Diversity, and a Diverse Array of Virulence Factors [PDF]

, 2017
Clostridium perfringens is an important cause of animal and human infections, however information about the genetic makeup of this pathogenic bacterium is currently limited.
Lindsay J. Hall, Purnima Pachori, Raymond Kiu, Raymond Kiu, Sarah Alexander, Shabhonam Caim   +5 more
core   +2 more sources