Results 231 to 240 of about 106,923 (262)

Fluorescent Nanodiamonds Based Theranostic Platform for pH‐Sensitive Drug Delivery and Quantum Sensing

Advanced Functional Materials, EarlyView.
A multifunctional nanodiamond platform enables pH‐triggered Diazoxide (DZX) delivery and quantum sensing of subcellular radical dynamics in triple‐negative breast cancer cells. Diamond relaxometry revealed reduced lysosomal radicals during DZX‐induced mitochondrial radical elevation, providing insights into redox modulation and organelle‐ resolved ...
Kaiqui Wu, Siyu Fan, Yue Zhang, Willem Woudstra, Thomas Mulder, Laurens Boscher Navarro, Jur van Dijken, Katja Loos, Romana Schirhagl   +8 more
wiley   +1 more source

Stabilized Full-Length Measles Fusion Protein Elicits Potent Immunity and Protection In Vivo

Zyla DS, Zipursky G, Marca RD, Lacarbonara D, Niemeyer G, Peng W, Predella C, Stearns K, Leedale C, Miller J, Tay D, Kao J, Acciani M, Di Clemente L, Das A, Parekh D, Avalos RD, McGill G, Dorrello NV, Hastie KM, Alabi CA, Snijder J, Moscona A, Greninger AL, Niewiesk S, Saphire EO, Porotto M.   +26 more
europepmc   +1 more source

Reducing Small Molecule Adsorption in a PDMS-Based Microphysiological System of the Female Reproductive Tract via Parylene-C Coating to Improve Mechanistic Studies. [PDF]

ACS Appl Mater Interfaces
Cherukuri R, Kim S, Moyer HL, Jesse H, Lam PY, Richardson LS, Kammala AK, Menon R, Rusyn I, Han A.   +9 more
europepmc   +1 more source

Light‐Responsive Enzyme‐Loaded Nanoparticles for Tunable Adhesion and Mechanical Wound Contraction

Advanced Functional Materials, EarlyView.
This study presents a photoactivatable enzyme‐loaded mesoporous nanoparticle system (MPDA_PaTy) that enables light‐triggered tunable tissue adhesion and facilitates mechanical wound contraction. Controlled enzymatic crosslinking at tissue or hydrogel interfaces allows on‐demand adhesion.
Junghyeon Ko, Hyeon‐Jin Kim, Jeong‐Uk Kim, Seh Ri Oh, Tae Hoon Kang, Junghwan Byun, Uk‐Jae Lee, Minglin Ma, Su‐Hwan Kim, Byung‐Gee Kim, Nathaniel S. Hwang   +10 more
wiley   +1 more source

An <i>In Vitro</i> Assessment of a Biopolymer-Based Medical Foam for Enhanced Antifibrinolytic and Infection Prophylaxis for Acute Wound Management. [PDF]

ACS Appl Bio Mater
Stoner AK, Pezzanite LM, Dow SW, Alfonso NA, McGilvray KC.   +4 more
europepmc   +1 more source

A 3D Biofabricated Disease Model Mimicking the Brain Extracellular Matrix Suitable to Characterize Intrinsic Neuronal Network Alterations in the Presence of a Breast Tumor Disseminated to the Brain

Advanced Functional Materials, EarlyView.
A 3D disease model is developed using customized hyaluronic‐acid‐based hydrogels supplemented with extracellular matrix (ECM) proteins resembling brain ECM properties. Neurons, astrocytes, and tumor cells are used to mimic the native brain surrounding.
Esra Türker, Mateo S. Andrade Mier, Jessica Faber, Mike Friedrich, Zan Lamberger, Jeannette Weigelt, Christian Stigloher, Nicoletta Murenu, Natascha Schaefer, Jörg Tessmar, Gregor Lang, Silvia Budday, Katrin G. Heinze, Antje Appelt‐Menzel, Pamela L. Strissel, Reiner Strick, Carmen Villmann   +16 more
wiley   +1 more source

Better understanding of laboratory animal genetics will improve reproducibility. [PDF]

PLoS Biol
Pavlovic G, Wells S, Hérault Y, Teboul L.   +3 more
europepmc   +1 more source

Path dependency and the rescuing of the biomedical research enterprise. [PDF]

Front Med Technol
Nahle Z.
europepmc   +1 more source

The role of bioinformatics algorithms in modern biopharmaceutical design: Progress, challenges, and future perspectives. [PDF]

Bioimpacts
Pourseif MM, Baradaran Hosseini SA, Khoshraftar SH, Omidi Y.   +3 more
europepmc   +1 more source

Kaempferitrin Attenuates Lipopolysaccharide-Induced Cardiac Dysfunction Through Suppression of the NF-κB/NLRP3 Signaling Pathway. [PDF]

Immun Inflamm Dis
Kuang H, Li Q, Chen M, Du H.
europepmc   +1 more source