Results 91 to 100 of about 5,332,863 (278)
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Animal, 2011 Dairy herd size is expected to increase in many European countries, given the recent policy changes within the European Union. Managing more cows may have implications for herd performance in the post-quota era.
J.G. Jago, D.P. Berry
doaj +1 more source
Theoretical Computer Science, 2020 An Automata Network is a map ${f:Q^n\rightarrow Q^n}$ where $Q$ is a finite alphabet. It can be viewed as a network of $n$ entities, each holding a state from $Q$, and evolving according to a deterministic synchronous update rule in such a way that each entity only depends on its neighbors in the network's graph, called interaction graph. A major trend
Bridoux, Florian +2 more
openaire +4 more sources
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
The Encyclopedia of Ancient History: Asia and Africa, 2023 The Bantu expansion is the initial spread of the Bantu languages and the people speaking them from their original homeland in the border zone of modern‐day Nigeria and Cameroon over major parts of eastern and central Africa. This entry reviews the key evidence from historical linguistics, evolutionary genetics, and archaeology for this major demic ...
openaire +2 more sources
Fatgraph expansion for noncritical superstrings [PDF]
, 2004 We study the fatgraph expansion for the Complex Matrix Quantum Mechanics (CMQM) with a Chern-Simons coupling. In the double-scaling limit this model is believed to describe Type 0A superstrings in 1+1 dimensions in a Ramond-Ramond electric field.
Kapustin, Anton, Murugan, Arvind
core +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Frontiers in Human NeuroscienceThe evolutionary adaptation of the left inferior frontal gyrus is considered a crucial neural specialization supporting the emergence of human language.
Jinyi Zhang +5 more
doaj +1 more source
EUROPEAN NEIGHBOURHOOD POLICY: EVOLUTION AND PRIORITIES [PDF]
Economica, 2019 The article analyses the evolution and changes made in the European Neighbourhood Policy (ENP) since its launch in 2004. It shows that the change of the socio-economic situation and a series of conflicts in the neighbourhood of the European Union ...
Natalia LOBANOV
doaj