Results 81 to 90 of about 1,227,011 (269)

Expansions of Nanotechnology

, 2012
Little by little, nanotechnology has emerged amid enormous aspirations for newmaterials and fantastic promises of manipulating our world “atom by atom.” Whilethese grand visions continue to capture the imaginations of various audiences—andcontinue to be contested, as well—nanotechnology has developed into more than that.During the last two decades ...
van Lente, Harro, Coenen, Christopher, Fleischer, Torsten, Konrad, Kornelia, Krabbenborg, Lotte, Milburn, Colin, Thoreau, François, Zülsdorf, Torben   +7 more
openaire   +4 more sources

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

FEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Asymmetric Evolution and Expansion of the NAC Transcription Factor in Polyploidized Cotton

Frontiers in Plant Science, 2018
Polyploidy in Gossypium hirsutum conferred different properties from its diploid ancestors under the regulation of transcription factors. The NAC transcription factor is a plant-specific family that can be related to plant growth and development. So far,
Kai Fan, Kai Fan, Kai Fan, Feng Li, Jiahuan Chen, Jiahuan Chen, Jiahuan Chen, Zhaowei Li, Zhaowei Li, Weiwei Lin, Weiwei Lin, Size Cai, Size Cai, Size Cai, Jianping Liu, Jianping Liu, Wenxiong Lin, Wenxiong Lin, Wenxiong Lin   +18 more
doaj   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

FEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

I viaggi del 1949 in Sicilia nelle relazioni di Luigi Tirelli / The Trips to Sicily in 1949 Based on Notes by Luigi Tirelli [PDF]

Studia et Documenta
The first expansion of Opus Dei in Italy, in 1949, is described: this consists of an overview together with the criteria given by St. Josemaría for undertaking the trips to make Opus Dei known.
Cosimo Di Fazio
doaj   +1 more source

Ubiquitination of secretory granules promotes their crinophagic degradation in Drosophila

FEBS Letters, EarlyView.
Ubiquitination of secretory granules in Drosophila larval salivary glands is a critical molecular trigger for crinophagy, the lysosomal degradation of unreleased, or low‐quality granules. The E3 ubiquitin ligase Cnot4 is recruited to the surface of secretory granules to induce crinophagy.
Tamás Csizmadia, Anna Dósa, Asha Kiran Maddali, András Jipa, Hajnalka Laczkó‐Dobos, Péter Lőw, Gábor Juhász   +6 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

THE CREATION OF ANALYTICAL PREDICATION CONCEPT IN MULTILEVEL ORGANIZATION SYSTEM MANAGEMENT

Модернизация, инновация, развитие, 2015
This article deals with analytical and forecasting methodology problems in the integrated business systems management. The theoretical framework of analytical predication concept in multilevel organization systems is presented.
O. M. Pisareva
doaj