IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo +6 more
wiley +1 more source
Spatiotemporal analysis of urban expansion and environmental impacts in five Saudi Arabian cities by utilizing geospatial and remote sensing approach. [PDF]
Shohan AAA +6 more
europepmc +1 more source
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley +1 more source
Racial differences in multiple myeloma survival: Associations with stem cell transplantation, insurance, and Medicaid expansion. [PDF]
Wong FL +5 more
europepmc +1 more source
Yeast Gcn2 retains activity following humanization of its auto‐phosphorylation region
Using Saccharomyces cerevisiae as a model to study Gcn2 activation and regulation is limited by the lack of antibodies detecting phosphorylated Gcn2. To overcome this, we engineered Gcn2‐HsC, a yeast Gcn2 variant recognizable by commercial anti‐human phospho‐GCN2 antibodies.
Reuben A. Anderson +2 more
wiley +1 more source
Quantifying CAHOOTS: Measuring a mobile crisis response program's impact on police response through call diversion and prevention. [PDF]
Burton N, Herbert C, Rohlfs R.
europepmc +1 more source
MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss +7 more
wiley +1 more source
Medicaid Expansion and Mortality Among Patients With Colorectal Cancer.
Akinyemi O +11 more
europepmc +1 more source
Spatiotemporal CD8<sup>+</sup> T-Cell Dynamics: Clonal Replacement and Expansion as Determinants of Sustainable Antitumor Response. [PDF]
Ueha S +4 more
europepmc +1 more source

