Results 81 to 90 of about 1,225,639 (301)

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

Proactive transmission expansion planning with storage considerations

open access: yesEnergy Strategy Reviews, 2019
Under the current European market environment, transmission companies have to decide network expansion by maximizing social welfare. However, generation companies (GENCOs) decide their capacity expansion with the aim of maximizing their own profit.
Isaac-Camilo Gonzalez-Romero   +2 more
doaj   +1 more source

Small-Scale Irrigation Mapping (SSIM) as a tool for improving and validating irrigated area maps: contextual approach and lessons learnt in Burkina Faso [PDF]

open access: yes, 2020
Recent rapid expansion of private small-scale irrigation provides an opportunity to improve livelihoods and food security, but requires knowledge of where it is happening, in order to sustainably manage water use.
Barron, Jennie   +2 more
core  

Applicability of mitotic figure counting by deep learning: a development and pan‐cancer validation study

open access: yesFEBS Open Bio, EarlyView.
In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes   +32 more
wiley   +1 more source

Distributed Resources Shift Paradigms on Power System Design, Planning, and Operation: An Application of the GAP Model [PDF]

open access: yes, 2019
Power systems have evolved following a century-old paradigm of planning and operating a grid based on large central generation plants connected to load centers through a transmission grid and distribution lines with radial flows.
Callaway, D   +3 more
core  

Impact of Forecast Errors on Expansion Planning of Power Systems with a Renewables Target

open access: yes, 2014
This paper analyzes the impact of production forecast errors on the expansion planning of a power system and investigates the influence of market design to facilitate the integration of renewable generation.
Boomsma, Trine Krogh   +2 more
core   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

open access: yesFEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner   +7 more
wiley   +1 more source

Transmission and Generation Expansion Planning Considering Virtual Power Lines/Plants, Distributed Energy Injection and Demand Response Flexibility from TSO-DSO Interface

open access: yesEnergies
This article presents a computational model for transmission and generation expansion planning considering the impact of virtual power lines, which consists of the investment in energy storage in the transmission system as well as being able to determine
Flávio Arthur Leal Ferreira   +2 more
doaj   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

NDC plans expansion

open access: yes, 2018
coverage: Dar es ...
openaire   +2 more sources

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