Results 101 to 110 of about 4,612,820 (291)
Prediction of Hole Expansion Ratio for Advanced High-Strength Steel with Image Feature Analysis of Sheared Edge. [PDF]
Materials (Basel), 2023 Jeong K, Jeong Y, Lee J, Won C, Yoon J.
europepmc +1 more source
Molecular Oncology, EarlyView.The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington +10 more
wiley +1 more source
Integrated Machine Vision System for Evaluating Hole Expansion Ratio of Advanced High-Strength Steels. [PDF]
Materials (Basel), 2022 Park J, Won C, Lee HJ, Yoon J.
europepmc +1 more source
CEACAM1 participation in breast cancer progression
Molecular Oncology, EarlyView.In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
High-Strength Bio-Degradable Polymer Foams with Stable High Volume-Expansion Ratio Using Chain Extension and Green Supercritical Mixed-Gas Foaming. [PDF]
Polymers (Basel), 2023 Long H +9 more
europepmc +1 more source
A Constructal law perspective of cancer’s volume/area expansion ratio
, 2023 Constructal law is used to improve the analysis of the resonant heat transfer in cancer cells. The result highlights the fundamental role of the volume/area ratio and of its role in cancer growth and invasion.
Grisolia, G. +3 more
core
Molecular Oncology, EarlyView.Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou +4 more
wiley +1 more source
New Contour Design Method for Rocket Nozzle of Large Area Ratio
International Journal of Aerospace Engineering, 2019 A rocket engine for space propulsion usually has a nozzle of a large exit area ratio. The nozzle efficiency is greatly affected by the nozzle contour.
Dechuan Sun, Tianyou Luo, Qiang Feng
doaj +1 more source
Molecular Oncology, EarlyView.This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic +10 more
wiley +1 more source