Results 81 to 90 of about 516,507 (263)

Re-Examining Confidence Intervals for Ratios of Parameters

Econometrics
This paper considers the problem of constructing confidence intervals (CIs) for nonlinear functions of parameters, particularly ratios of parameters a common issue in econometrics and statistics.
Zaka Ratsimalahelo
doaj   +1 more source

NEW ASYMPTOTIC EXPANSIONS AND INEQUALITIES FOR MILLS RATIO

Journal of Science and Arts
This paper gives new asymptotic expansions for Mills ratio, and then establishes new inequalities for Mills ratio.
JUN-LING SUN, CHAO-PING CHEN, CRISTINEL MORTICI   +2 more
openaire   +1 more source

Integrated Machine Vision System for Evaluating Hole Expansion Ratio of Advanced High-Strength Steels. [PDF]

Materials (Basel), 2022
Park J, Won C, Lee HJ, Yoon J.
europepmc   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

High-Strength Bio-Degradable Polymer Foams with Stable High Volume-Expansion Ratio Using Chain Extension and Green Supercritical Mixed-Gas Foaming. [PDF]

Polymers (Basel), 2023
Long H, Xu H, Shaoyu J, Jiang T, Zhuang W, Li M, Jin J, Ji L, Ying H, Zhu C.   +9 more
europepmc   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

Molecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder, Klaas de Lint, Hồ Mỹ Phúc Võ, Mariana M. Góis, Rosalie A. Kampen, Marta San Martin Alonso, Ilse Nootenboom, Veronica Garzero, Tiemen J. Wendel, Rob M. F. Wolthuis, Sylvie M. Noordermeer   +10 more
wiley   +1 more source

Thermal expansion properties of the polycaprolactam nanocomposites reinforced with single-walled carbon nanotubes

Results in Physics, 2019
The effect of carbon nanotube loading and aspect ratio on the thermal expansion properties of polymer nanocomposites was investigated in terms of the material properties, configuration, and phase geometry of each individual component.
Junjie Chen, Jiecheng Han, Deguang Xu
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

New Contour Design Method for Rocket Nozzle of Large Area Ratio

International Journal of Aerospace Engineering, 2019
A rocket engine for space propulsion usually has a nozzle of a large exit area ratio. The nozzle efficiency is greatly affected by the nozzle contour.
Dechuan Sun, Tianyou Luo, Qiang Feng
doaj   +1 more source