Results 71 to 80 of about 8,179,783 (370)

Optimizing interleukin-2 concentration, seeding density and bead-to-cell ratio of T-cell expansion for adoptive immunotherapy

BMC Immunology, 2021
Background The successful ex vivo expansion of T-cells in great numbers is the cornerstone of adoptive cell therapy. We aimed to achieve the most optimal T-cell expansion condition by comparing the expansion of T-cells at various seeding densities, IL-2 ...
Sasan Ghaffari, Monireh Torabi‐Rahvar, S. Aghayan, Zahra Jabbarpour, K. Moradzadeh, A. Omidkhoda, N. Ahmadbeigi   +6 more
semanticscholar   +1 more source

Clinical Characteristics and Prognostic Risk Factors for Pediatric B‐Cell Lymphoblastic Lymphoma: A Multicenter Retrospective Cohort Study for China Net Childhood Lymphoma

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background B‐cell lymphoblastic lymphoma (B‐LBL) represents a rare variety of non‐Hodgkin lymphoma, with limited research on its biology, progression, and management. Methods A retrospective analysis was performed on the clinical characteristics of 256 patients aged ≤18 years who received treatment under the China Net Childhood Lymphoma (CNCL)‐
Zhijuan Liu, Jian Wang, Ling Jin, Yanlong Duan, Fu Li, Yueping Jia, Leping Zhang, Xiaojun Yuan, Wei Liu, Ying Liu, Ansheng Liu, Mincui Zheng, Yunpeng Dai, Lian Jiang, Lirong Sun, Xiaowen Zhai, Rong Liu, Chunju Zhou, Zifen Gao, Yonghong Zhang, Xiaomei Yang   +20 more
wiley   +1 more source

Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM

FEBS Letters, EarlyView.
Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley   +1 more source

Perturbation solutions for a micropolar fluid flow in a semi-infinite expanding or contracting pipe with large injection or suction through porous wall

Open Physics, 2016
We investigate an unsteady incompressible laminar micropolar flow in a semi-infinite porous pipe with large injection or suction through a deforming pipe wall.
Si Xinhui, Yuan Lili, Cao Limei, Zheng Liancun, Shen Yanan, Li Lin   +5 more
doaj   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Expansion potential of novel skin grafts simulants with I-shaped auxetic incisions

Biomedical Engineering Advances, 2023
Skin grafts play an important role in treatment of severe burn injuries. Split-thickness skin grafting is one of the most common grafting technique, in which, parallel incision patterns are projected onto a small portion of excised skin for generating ...
Vivek Gupta, Arnab Chanda
doaj   +1 more source

Recent results in chiral effective field theory for the NN system [PDF]

, 2013
I describe recent progress towards a theory of the NN force which captures the consequences of QCD's chiral symmetry and the pattern of its breaking, and is formulated as an expansion in a ratio of low and high mass scales, M_{lo}/M_{hi}.
Phillips, Daniel R.
core   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Multistage axial hydro-forging sequence of double-stepped tube with large expansion ratio

International Journal of Lightweight Materials and Manufacture, 2020
In order to manufacture the double-stepped tube with large expansion ratio, a multistage axial hydro-forging sequence was proposed by combination of hydroforming with movable dies in this paper. The new forming process is divided into four stages. In the
Lei Sun, Caiyuan Lin, Guodong Wang, Guannan Chu   +3 more
doaj   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source