Results 191 to 200 of about 534,089 (316)

Placebo, nocebo: Believing in the field of medicine

Frontiers in Pain Research, 2022
Karin Meissner, Karin Meissner
doaj   +1 more source

Expectation Violation Influences Neural Responses to the Accessibility of Cognitions Related to Suicide and Life: A Simultaneous EEG-fNIRS Study. [PDF]

Brain Sci
Liu B, Wu Y, Jin T, Lei Z.
europepmc   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Do Elderly Patients Achieve Comparable Functional and Quality-of-Life Improvements After Anterior Cervical Discectomy and Fusion for Degenerative Cervical Myelopathy? [PDF]

Global Spine J
Lim JTE, Zeng GJ, Goh GS, Liow MHL, Soh RCC, Guo CM, Chen JL.   +6 more
europepmc   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Longitudinal assessment and clinical implications of treatment expectations in an outpatient pain centre: evaluation of the GEEE in patients with chronic pain. [PDF]

BMJ Open
Henrich L, Basedow LA, Maser D, Schmidt K, Bingel U, Rief W.   +5 more
europepmc   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

A Conceptual Framework for Understanding Patient Expectations in Individualised Anaesthesia and Analgesia: A Narrative Review and Future Directions. [PDF]

J Pers Med
Mogianos K, Persson AKM.
europepmc   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

Use of complementary therapies is associated with expectations of treatment effectiveness among persons with multiple sclerosis. [PDF]

BMJ Neurol Open
Stanikić M, Steinemann N, López-Alcalde J, Canella C, Barth J, Chan A, Roth P, Calabrese P, Zecca C, Gobbi C, Manjaly ZM, Ammann S, Kägi S, Baum C, Kamm CP, Puhan MA, Witt CM, von Wyl V, Swiss Multiple Sclerosis Registry.   +18 more
europepmc   +1 more source