Results 241 to 250 of about 2,292,196 (319)

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Modulating Placebo Effects in Clinical Trials: Study Team Briefing to Optimize Drug-Placebo Differences. [PDF]

Clin Transl Sci
Coenen M, Bingel U, Soledad Berdaguer M, Fuhrmann C, Németh R, Rengelshausen J, Hartmann G, Coch C, Schedlowski M.   +8 more
europepmc   +1 more source

Thresholds and expectation thresholds [PDF]

Gil Kalai, Jeff Kahn
core  

Safe Expectations

Academic Medicine, 2011
Dianne P, Wagner, Mary M, Noel, Henry C, Barry, Christopher B, Reznich   +3 more
openaire   +3 more sources

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

Molecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source

Women's Satisfaction with Gynecological Healthcare Services in a Public Tertiary Facility: A Questionnaire Study. [PDF]

Healthcare (Basel)
Gawron I, Derbisz K, Trojnarska D, Zaborowska L, Ludwin I, Ludwin A.   +5 more
europepmc   +1 more source

Alternating conditional expectation (ACE) algorithm and supervised classification models for rapid determination and classification of the adulterated cinnamon samples using diffuse reflectance FT-IR spectroscopy

Zahra S. Hajiseyedrazi, Mohammadreza Khanmohammadi, Mahsa Mohammadi   +2 more
openalex   +1 more source

The Customer Expectation and Satisfaction on Online Food Order From Restaurant in Chennai

, 2019
J Andrews, Smith Daniel, C, Jin Hee, Hur, Kyung Ha, Lee, Jung Ho, Choo, Perianayagam Jesudoss, Sharda Haryani, Bharti Motwani, Sonal Kureshi, Vandana Sood   +13 more
openalex   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

On a result of K. P. Hart about non-existence of measurable solutions to the discrete expectation maximization problem [PDF]

Vladimir Pestov
openalex   +1 more source