Results 241 to 250 of about 720,223 (381)

Identification of inhibitors of the Salmonella FraB deglycase, a drug target

FEBS Open Bio, EarlyView.
A high‐throughput screen was used to identify inhibitors of Salmonella FraB, a drug target. Characterization of top hits (identified after an additional counter screen) revealed that some triazolidines, thiadiazolidines, and triazolothiadiazoles are mixed‐type inhibitors of FraB.
Jamison D. Law, Yuan Gao, Sravya Kovvali, Pankajavalli Thirugnanasambantham, Vicki H. Wysocki, Brian M. M. Ahmer, Venkat Gopalan   +6 more
wiley   +1 more source

Rethinking the residual approach: leveraging statistical learning to operationalize cognitive resilience in Alzheimer's disease. [PDF]

Brain Inform
Birkenbihl C, Cuppels M, Boyle RT, Klinger HM, Langford O, Coughlan GT, Properzi MJ, Chhatwal J, Price JC, Schultz AP, Rentz DM, Amariglio RE, Johnson KA, Gottesman RF, Mukherjee S, Maruff P, Lim YY, Masters CL, Beiser A, Resnick SM, Hughes TM, Burnham S, Tunali I, Landau S, Cohen AD, Johnson SC, Betthauser TJ, Seshadri S, Lockhart SN, O'Bryant SE, Vemuri P, Sperling RA, Hohman TJ, Donohue MC, Buckley RF.   +34 more
europepmc   +1 more source

COMPARISON OF OPINIONS ON PRE-SCHOOL EDUCATION AND DEVELOPMENTAL EXPECTATION BETWEEN JAPANESE AND AMERICAN MOTHERS

, 1977
Keiko Kashiwagi, Hiroshi Azuma
openalex   +2 more sources

Great expectations [PDF]

Sao Paulo Medical Journal, 2012
Pêgo-Fernandes, Paulo Manuel, Bibas, Benoit Jacques   +1 more
openaire   +4 more sources

Beyond digital twins: the role of foundation models in enhancing the interpretability of multiomics modalities in precision medicine

FEBS Open Bio, EarlyView.
This review highlights how foundation models enhance predictive healthcare by integrating advanced digital twin modeling with multiomics and biomedical data. This approach supports disease management, risk assessment, and personalized medicine, with the goal of optimizing health outcomes through adaptive, interpretable digital simulations, accessible ...
Sakhaa Alsaedi, Xin Gao, Takashi Gojobori   +2 more
wiley   +1 more source

Understanding the influencing mechanism of continuance utilization of rehabilitation services among children with disabilities: a cross-sectional survey in two cities of China. [PDF]

BMC Public Health
Xia C, Wei T, Shao P, Tang Q, Zheng H, Sun M, Chen G, Lu J.   +7 more
europepmc   +1 more source

Faculty role expectation

, 1977
Gerald D. Otis
openalex   +1 more source

Acacetin reduces endoplasmic reticulum stress through the P‐eNOS/PERK signaling pathway to attenuate MGO‐induced vascular endothelial cell dysfunction

FEBS Open Bio, EarlyView.
We investigated a potential protective effect of acacetin, a naturally occurring flavonoid, against methylglyoxal (MGO)‐induced endothelial dysfunction in human umbilical vein endothelial cells and its mechanism of action. Acacetin can could inhibit MGO‐induced intracellular calcium ion influx, enhance the expression levels of phosphorylated ...
Zhen Zhang, Kaien Hu, Zhaohui Fang, Sihai Wang, Jie Chen, Dengke Yin, Caiyun Zhang, Gefei Ma   +7 more
wiley   +1 more source

Placebo treatment entails resource-dependent downregulation of negative inputs. [PDF]

Sci Rep
Mostauli A, Rauh J, Gamer M, Büchel C, Rief W, Brassen S.   +5 more
europepmc   +1 more source

Differential effects of prestructuring client's expectation of counselor empathy on client's anxiety and evaluation of the counselor using two types of analogues

, 1975
Janet E. Helms
openalex   +2 more sources