Results 91 to 100 of about 5,035,408 (306)
Радиационная гигиена, 2015 An article contains the analysis of the main expected changes in the setting standards of population exposure from natural sources in connection with the publication of the new IAEA standard «Protection of the Public against Exposure Indoors due to ...
I. P. Stamat
doaj
Frontiers in EpidemiologyTraditional methods for measuring chemical exposure have challenges in terms of obtaining sufficient data; therefore, improved methods for better assessing occupational exposure are needed.
Therese Klang +8 more
doaj +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Information about lead exposure in Clarksburg, West Virginia [PDF]
info-lead-exposure-clarksburg-wv-may-2022-508 ...
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Differential gene expression in relation to mating system in Peromyscine rodents
Ecology and Evolution, 2019 Behaviors that increase an individual's exposure to pathogens are expected to have important effects on immunoactivity. Because sexual reproduction typically requires close contact among conspecifics, mating systems provide an ideal opportunity to study ...
Jesyka Meléndez‐Rosa +2 more
doaj +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
NON-EXPECTED UTILITY THEORIES: WEIGHTED EXPECTED, RANK DEPENDENT, AND CUMULATIVE PROSPECT THEORY UTILITY [PDF]
This paper discusses some of the failings of expected utility including the Allais paradox and expected utility's inadequate one dimensional characterization of risk.
Tuthill, Jonathan W. +1 more
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Short-Term Outcomes of KeraSys Patch Graft for Glaucoma Drainage Devices: A Case Series
Journal of Ophthalmology, 2013 Purpose. Tube-related exposure is a known complication of glaucoma drainage device (GDD) surgery. Our objective is to report the early (approximately 1 year) tube exposure rate of implants covered with a keraSys (IOP Inc., Costa Mesa, CA, USA) tissue ...
Kundandeep S. Nagi +7 more
doaj +1 more source
South African Family Practice, 2007 Background: The possibility of occupational exposure to bloodborne viruses such as HIV, hepatitis B virus (HBV) and hepatitis C virus (HCV) is an everyday reality for healthcare workers.
H.C. de Villiers +2 more
doaj +1 more source
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source