Results 231 to 240 of about 2,746,744 (357)

A Bootstrap Equality Test for Value at Risk and Expected Shortfall

Mario Maggi, Pierpaolo Uberti
openalex   +1 more source

Extended Duration of Training, Resident Physician Well-being, and the Primary Care Physician Shortage: Questions Remaining Following the Length of Training Pilot. [PDF]

Fam Med
Parente DJ.
europepmc   +1 more source

The Gut Microbiota Regulates Motor Deficits via Butyrate in a Gnal+/− Mouse Model of DYT25 Dystonia

Advanced Science, EarlyView.
The present study provides compelling evidence for a modulatory role of the gut microbiota in the pathology of DYT25 dystonia, and butyrate supplementation alleviates the motor deficits of dystonia in Gnal+/− mice. Abstract Dystonia is the third most common movement disorder, following essential tremor and Parkinson's disease. The underlying mechanisms
Jingya Guo, Seong‐Gook Kang, Kunlun Huang, Tao Tong   +3 more
wiley   +1 more source

Sensitivity Analysis of VaR Expected Shortfall for Portfolios Under Netting Agreements

, 2003
Jean‐David Fermanian, Olivier Scaillet
openalex   +1 more source

Forecasting with a Bivariate Hysteretic Time Series Model Incorporating Asymmetric Volatility and Dynamic Correlations. [PDF]

Entropy (Basel)
Than HT.
europepmc   +1 more source

Dual Targeting of Tau Kinases and Autophagy by Abemaciclib Independent of CDK4/6 Inhibition

Advanced Science, EarlyView.
Abemaciclib rescues cognitive function and attenuates tau pathology in Alzheimer's disease models, but not through its known cancer‐fighting mechanism. This study demonstrates that abemaciclib operates independently of CDK4/6 inhibition, instead directly targeting tau kinases CaMKII and GSK3β while simultaneously promoting autophagic clearance of ...
Jihui Han, June‐Hyun Jeong, Dongjoon Lee, Yujin Jung, Yujin Jin, Eun Sun Jung, Haeng Jun Kim, Woo Youn Kim, Chang‐Han Lee, Inhee Mook‐Jung   +9 more
wiley   +1 more source

Semi-parametric Realized Nonlinear Conditional Autoregressive Expectile and Expected Shortfall [PDF]

, 2019
Chao Wang, Richard Gerlach
openalex   +1 more source

Cost-Effectiveness of Metoclopramide, Paracetamol, and Ceftriaxone for the Prevention of Infections and Fever in Elderly Patients with Acute Stroke. [PDF]

MDM Policy Pract
Vervaart M, de Jonge JC, Bath PM, Melberg HO, Reinink H, Sluis WM, Woodhouse LJ, van der Worp HB, Aamodt AH, PRECIOUS Investigators.   +9 more
europepmc   +1 more source

Astrocytic PCBP1 Suppresses Ferroptosis to Restore Glutamatergic Homeostasis and Mitigate Stress‐Induced Depression in Male Mice

Advanced Science, EarlyView.
This study demonstrates that polyC‐RNA‐binding protein 1 (PCBP1) in ventral hippocampal astrocytes modulates depressive‐like behaviors by regulating glutathione peroxidase 4‐mediated ferroptosis and synaptic glutamatergic transmission. PCBP1 overexpression intervention in the chronic unpredictable mild stress model rescues behavioral deficits ...
Jinyu Zhang, Binbin Zhao, Min Jia, Yan Zhao, Ye Lu, Wenyu Xi, Ziyu Zhu, Xiaojuan Gong, Qingyan Ma, Yuan Gao, Yijie Guo, Pan Li, Feng Zhu, Shuguang Wei, Xiancang Ma, Yunpeng Wang   +15 more
wiley   +1 more source

Relative Bound and Asymptotic Comparison of Expectile with Respect to\n Expected Shortfall [PDF]

, 2019
Samuel Drapeau, Mekonnen Tadese
openalex   +1 more source