Donor‐derived tdTomato+ mature hepatocytes were FACS‐isolated and transplanted into Fah−/− host mice. During regeneration, these cells convert into proliferative, unipotent Afp+ rHeps. Their plasticity is governed by a PPARγ/AFP‐dependent metabolic switch, segregating into pro‐proliferative Afplow and pro‐survival Afphigh subpopulations.
Ting Fang +12 more
wiley +1 more source
Simultaneous Pancreas-Kidney Transplantation Vs. Deceased Donor Kidney Transplantation in Patients With Diabetes Mellitus - An Ongoing Controversy. [PDF]
Gruessner AC, Gruessner RWG.
europepmc +1 more source
Multifunctional Tailoring of Fertilizer Composites Directly Derived From Phosphate Rock
A novel phosphorus‑sulfur mixed acid with urea (PSU) activation system converts low‑grade phosphate rock (LPR) into multifunctional fertilizer composites (MFCs). MFCs feature porous structures, high nutrient‑activation efficiency, superior slow‑release, and enhanced crop growth, offering a sustainable solution for integrated nutrient management and ...
Zenglian Qi +13 more
wiley +1 more source
Expanding healthcare capacity in Canada: the potential of internationally trained physicians. [PDF]
Leiva Tobelem LF +2 more
europepmc +1 more source
Cytokine‐engineered CAR‐T cells represent a promising immunotherapy against malignancies due to direct tumor killing and potent immunity response. However, significant toxicities, including CRS and ICANS, have restricted clinical applications. How to keep the risk‐benefit balance of the advanced therapy is of great importance for maximizing the benefit
Xinru Zhang +7 more
wiley +1 more source
Optimal Portfolio Risk Estimation Using Expected Shortfall of Jakarta Islamic Index (JII) Shares
Adika Risky Lestari, Devni Prima Sari
openalex +2 more sources
Surgeons Outside of Cities: Longitudinal Trends in the Surgical Workforce of Rural Australia From 2013 to 2022. [PDF]
Edwards T +7 more
europepmc +1 more source
Microglial GPR35 Ameliorates Epileptogenesis and Neuroinflammation via PDGFA Domain 2 Signaling
Activation of microglial G protein–coupled receptor 35 (GPR35) by L‐kynurenic acid (L‐Kyna) initiates a platelet‐derived growth factor A (PDGFA)–dependent phosphoinositide 3‐kinase–protein kinase B (PI3K–AKT) signaling cascade that dampens hippocampal neuroinflammation, thereby restraining epileptogenesis, lowering seizure susceptibility, and ...
Qi Wang +17 more
wiley +1 more source
Expected shortfall assessment in commodity (L)ETF portfolios with semi-nonparametric specifications
Esther B. Del Brío +2 more
openalex +2 more sources
Turbulence drive and causal generation of vorticity in edge fusion plasmas. [PDF]
Dif-Pradalier G +11 more
europepmc +1 more source

