Results 41 to 50 of about 432,237 (304)

Pathogenic Germline PALB2 and RAD50 Variants in Patients With Relapsed Ewing Sarcoma

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Approximately 10% of patients with Ewing sarcoma (EwS) have pathogenic germline variants. Here, we report two cases: first, a novel germline pathogenic variant in partner and localizer of BRCA2 (PALB2) in a patient with a late EwS relapse. Its impact on homologous recombination is demonstrated, and breast cancer risk is discussed.
Molly Mack, A. Carolina Tufino, Mohd Azrin Jamalruddin, Sreya Dey, Yinghong Pan, Elina Mukherjee, Jessica D. Daley, Julia Meade, Mahmoud Aarabi, Lisa Maurer, James Cooper, Kara A. Bernstein, Kelly M. Bailey   +12 more
wiley   +1 more source

Developmental Disorders in Children Recently Diagnosed With Cancer

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Neurocognitive deficits in adult survivors of childhood cancer are well established, but less is known about developmental disorders (DD) arising shortly after cancer diagnosis. Using 2016–2019 linked Ohio cancer registry and Medicaid data, we compared DD among 324 children with cancer and 606,913 cancer‐free controls.
Jamie Shoag, Long Vu, Ritika Miryala, Jeffrey M. Albert, Molly McVoy, Siran M. Koroukian   +5 more
wiley   +1 more source

Teoria de la eleccion racional: estructura conceptual y evolucion reciente.

Colombia Internacional, 2005
This article hopes to facilitate dialogue within political studies by presenting a general description of the conceptual structure of Rational Choice Theory, RCT.
Felipe Botero., Pablo Abitbol.
doaj  

Multiattribute Utility Theory Without Expected Utility Foundations [PDF]

Operations Research, 1996
Methods for determining the form of utilities are needed for the implementation of utility theory in specific decisions. An important step forward was achieved when utility theorists characterized useful parametric families of utilities and simplifying decompositions of multiattribute utilities.
Wakker, P.P., Miyamoto, J.
openaire   +3 more sources

Characterizing Parental Concerns About Lasting Impacts of Treatment in Children With B‐Acute Lymphoblastic Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background B‐acute lymphoblastic leukemia (B‐ALL) is the most common pediatric cancer, and while most children in high‐resource settings are cured, therapy carries risks for long‐term toxicities. Understanding parents’ concerns about these late effects is essential to guide anticipatory support and inform evolving therapeutic approaches ...
Kellee N. Parker, Sarah W. Alexander, Lisa M. Jacola, Kimberly A. Buff, Kyobin Hwang, Elham Hashemi, Gregory Stoddard, Lindsay A. Jibb   +7 more
wiley   +1 more source

A Reflection on the Application of the Precautionary Principle in the Regulation of Genetically Modified (GM) Crops [PDF]

Pizhūhish/hā-yi Falsafī- Kalāmī
One of the most significant developments in molecular biology in the last few decades has been the genetic modification of various organisms with different genetic engineering technologies. In particular, biotechnology companies and research centers have
Hamed Bikaraan-Behesht
doaj   +1 more source

EU income stabilization tool: potential impacts, financial sustainability and farmer’s risk aversion

Agricultural and Food Economics, 2021
The Income Stabilization Tool, a risk management scheme introduced within the Common Agricultural Policy (CAP) 2014–2020, could help European Union farmers manage the income risks they face.
Simone Severini, Cinzia Zinnanti, Valeria Borsellino, Emanuele Schimmenti   +3 more
doaj   +1 more source

Considerations for Developing Predictive Spatial Models of Crime and New Methods for Measuring Their Accuracy

ISPRS International Journal of Geo-Information, 2021
A literature review of the important trends in predictive crime modeling and the existing measures of accuracy was undertaken. It highlighted the need for a robust, comprehensive and independent evaluation and the need to include complementary measures ...
Chaitanya Joshi, Sophie Curtis-Ham, Clayton D’Ath, Deane Searle   +3 more
doaj   +1 more source

Expected Information as Expected Utility

The Annals of Statistics, 1979
The normative procedure for the design of an experiment is to select a utility function, assess the probabilities, and to choose that design of maximum expected utility. One difficulty with this view is that a scientist typically does not have, nor can be normally expected to have, a clear idea of the utility of his results. An alternative is to design
openaire   +3 more sources

Predicting the Future Burden of Renal Replacement Therapy in Türkiye Using National Registry Data and Comparative Modeling Approaches

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic kidney disease is a growing public health problem worldwide, and the number of patients requiring renal replacement therapy is steadily increasing. Türkiye has experienced a similar rise in both the incidence and prevalence of renal replacement therapy over the past decades; however, national‐level projections of future ...
Arzu Akgül, Neriman Sıla Koç, Berrak Itır Aylı   +2 more
wiley   +1 more source