Results 41 to 50 of about 1,764,628 (294)

Profit-Driven Methodology for Servo Press Motion Selection under Material Variability

open access: yesApplied Sciences, 2021
Servo presses enable new types of forming motion profiles that can be used to stamp difficult materials, such as high strength steels. This paper presents an application of Bayesian statistics to intelligently select which motion profile maximizes the ...
Nozomu Okuda   +3 more
doaj   +1 more source

Forward-backward systems for expected utility maximization [PDF]

open access: yes, 2011
In this paper we deal with the utility maximization problem with a general utility function. We derive a new approach in which we reduce the utility maximization problem with general utility to the study of a fully-coupled Forward-Backward Stochastic ...
Horst, Ulrich   +4 more
core   +4 more sources

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

Unifying Speed-Accuracy Trade-Off and Cost-Benefit Trade-Off in Human Reaching Movements

open access: yesFrontiers in Human Neuroscience, 2017
Two basic trade-offs interact while our brain decides how to move our body. First, with the cost-benefit trade-off, the brain trades between the importance of moving faster toward a target that is more rewarding and the increased muscular cost resulting ...
Luka Peternel   +3 more
doaj   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Teoria de la eleccion racional: estructura conceptual y evolucion reciente.

open access: yesColombia Internacional, 2005
This article hopes to facilitate dialogue within political studies by presenting a general description of the conceptual structure of Rational Choice Theory, RCT.
Felipe Botero., Pablo Abitbol.
doaj  

The role of stimulus-driven versus goal-directed processes in fight and flight tendencies measured with motor evoked potentials induced by Transcranial Magnetic Stimulation [PDF]

open access: yes, 2019
This study examines two contrasting explanations for early tendencies to fight and flee. According to a stimulus-driven explanation, goal-incompatible stimuli that are easy/difficult to control lead to the tendency to fight/flee.
Bardi, Lara   +6 more
core   +2 more sources

Multiattribute Utility Theory Without Expected Utility Foundations [PDF]

open access: yesOperations Research, 1996
Methods for determining the form of utilities are needed for the implementation of utility theory in specific decisions. An important step forward was achieved when utility theorists characterized useful parametric families of utilities and simplifying decompositions of multiattribute utilities.
Wakker, P.P., Miyamoto, J.
openaire   +3 more sources

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Considerations for Developing Predictive Spatial Models of Crime and New Methods for Measuring Their Accuracy

open access: yesISPRS International Journal of Geo-Information, 2021
A literature review of the important trends in predictive crime modeling and the existing measures of accuracy was undertaken. It highlighted the need for a robust, comprehensive and independent evaluation and the need to include complementary measures ...
Chaitanya Joshi   +3 more
doaj   +1 more source

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