Results 61 to 70 of about 486,742 (215)
Understanding Russian aggression towards Georgia
Politikon, 2012 Did Russia initiate conflict with Georgia in an attempt to restrain Georgia from formally joining the Western coalition, or was the decision more complex? What did Russia hope to gain from initiating conflict? What value did Russia assign to maintaining
Michael J. Langlois
doaj +1 more source
Structural and biochemical analysis of a B12 superbinder
FEBS Letters, EarlyView.BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Ergo, An Open Access Journal of PhilosophyA moral requirement R1 is said to be lexically prior to a moral requirement R2 just in case we are morally obliged to uphold R1 at the expense of R2—no matter how many times R2 must be violated thereby. While lexical priority is a feature of many ethical
Martin Smith
doaj +2 more sources
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Filozofická reflexe omezené racionality (Philosophical Reflection of Bounded Rationality )
Ostium, 2017 Research of rationality represents area of interaction between philosophy and economics. Development of neuroscience and advances in scientific research lead to another common characteristic – gradual loss of competence to comment on results of ...
Michal Müller, Ondrej Močkor
doaj
Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers
FEBS Letters, EarlyView.Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui +4 more
wiley +1 more source
FEBS Letters, EarlyView.Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil +3 more
wiley +1 more source
World Electric Vehicle JournalThe global automotive industry’ s rapid transformation has led to electric vehicles (EVs) capturing a significant market share as a sustainable transportation option.
Xiao Zheng +3 more
doaj +1 more source
Convergence of optimal expected utility for a sequence of binomial models. [PDF]
Math Financ, 2021 Hubalek F, Schachermayer W.
europepmc +1 more source