Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
CONSISTENT DYNAMICE CHOICE AND NON-EXPECTED UTILITY PREFERENCES [PDF]
Pursuing works from Sarin and Wakker (1998), we study how NonExpected Utility models could be consistently applied to multi-stage decision problems. Concerning multiple priors model, we remove the argument that dynamic consistency, consequentialism and ...
André Lapied, Pascal Tocquebeuf
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Evolution of non-expected utility preferences [PDF]
von Widekind S. Evolution of non-expected utility preferences. Working Papers. Institute of Mathematical Economics. Vol 370. Bielefeld: Universität Bielefeld; 2005.We investigate an extension of Dekel, Ely and Yilankaya's (2004) treatment of the ...
von Widekind, Sven
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Robust Portfolio Choice under the Modified Constant Elasticity of Variance
This study investigates ambiguity aversion within the framework of a utility-maximizing investor under a modified constant-elasticity-of-volatility (M-CEV) model for the underlying asset.
Wei Li Fan, Marcos Escobar Anel
doaj +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
A Single-Stage Approach to Anscombe and Aumann's Expected Utility [PDF]
expected utility theory;decision analysis;revealed ...
Wakker, P.P., Sarin, R.
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Decision Uncertainty from Strict Preferences in Sequential Search Scenarios with Multiple Criteria
The standard expected utility model applied by economists and decision scientists assumes both that decision makers (DMs) are rational and that their information retrieval behavior and choices are determined by the observed and potential values of the ...
Debora Di Caprio +2 more
doaj +1 more source
Is the crop insurance program effective in China? Evidence from farmers analysis in five provinces
This paper aims to evaluate the effectiveness of the Chinese crop insurance program in terms of farmers' utility and welfare. A simulation model based on the power utility function was first developed to evaluate the effectiveness of crop insurance. Then,
Ke WANG +3 more
doaj +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Calibration results for rank-dependent expected utility [PDF]
If its utility function is everywhere increasing and concave, rank-dependent expected utility shares a troubling property with expected utility aversion to the same moderate-stakes risk at every wealth level implies an extreme aversion to large-stakes ...
William Neilson
core

