Results 81 to 90 of about 432,237 (304)

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira   +14 more
wiley   +1 more source

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

open access: yesMolecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy   +9 more
wiley   +1 more source

Filozofická reflexe omezené racionality (Philosophical Reflection of Bounded Rationality )

open access: yesOstium, 2017
Research of rationality represents area of interaction between philosophy and economics. Development of neuroscience and advances in scientific research lead to another common characteristic – gradual loss of competence to comment on results of ...
Michal Müller, Ondrej Močkor
doaj  

Emerging role of ARHGAP29 in melanoma cell phenotype switching

open access: yesMolecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster   +3 more
wiley   +1 more source

Preferences for shifts in probabilities and expected utility theory

open access: yesEstudios Económicos, 2007
Las preferencias definidas sobre loterías inducen preferencias sobre cambios en probabilidades. Definimos el axioma de independencia para preferencias definidas sobre cambios en probabilidades. Al usar esta versión del axioma de independencia construimos
David Cantalá
doaj  

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

open access: yesMolecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici   +8 more
wiley   +1 more source

Effects of the GM Controversy on Iowa Corn-Soybean Farmers' Acreage Allocation Decisions

open access: yesJournal of Agricultural and Resource Economics, 2003
Prior to the 2000 planting season, some industry observers predicted acreage of genetically modified crops would decline dramatically. However, actual 2000 plantings presented a puzzle.
Corinne E. Alexander   +2 more
doaj   +1 more source

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