Results 31 to 40 of about 973,446 (295)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Genetic factors of individual differences in decision making in economic behavior: A Japanese twin study using the Allais problem

Frontiers in Psychology, 2015
Why does decision making differ among individuals? People sometimes make seemingly inconsistent decisions with lower expected (monetary) utility even when objective information of probabilities and rewards are provided.
Chizuru eShikishima, Kai eHiraishi, Shinji eYamagata, Juko eAndo, Mitsuhiro eOkada   +4 more
doaj   +1 more source

What Is True Halving in the Payoff Matrix of Game Theory? [PDF]

PLoS ONE, 2016
In game theory, there are two social interpretations of rewards (payoffs) for decision-making strategies: (1) the interpretation based on the utility criterion derived from expected utility theory and (2) the interpretation based on the quantitative ...
Hiromu Ito, Yuki Katsumata, Eisuke Hasegawa, Jin Yoshimura   +3 more
doaj   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Robo Advising and Investor Profiling

FinTech
The rise of digital technology and artificial intelligence has led to a significant change in the way financial services are delivered. One such development is the emergence of robo advising, which is an automated investment advisory service that ...
Raquel M. Gaspar, Madalena Oliveira
doaj   +1 more source

RISK AVERSION AND MOTOR INSURANCE DEMAND: EMPIRICAL EVIDENCE FROM NIGERIA [PDF]

Annals of the University of Craiova: Economic Sciences Series, 2019
Insurance demand is often pushed by high level aversion of risk. Risk aversion is seen as the heartbeat of the demand for insurance. Therefore, this study examined the relationships between risk aversion and insurance demand with its empirical findings ...
Sunday Stephen AJEMUNIGBOHUN, Sulaiman Ademola Oreshile   +1 more
doaj  

μ–σ Games

Games, 2021
Risk aversion in game theory is usually modeled using expected utility, which was criticized early on, leading to an extensive literature on generalized expected utility.
Uwe Dulleck, Andreas Löffler
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

From Expected Utility Theory to Prospect Theory : Tracking Down the Experimental Path After Forty Years

Operations Research and Decisions, 2020
The expected utility theory axioms have been studied experimentally. Three of the experiments are a repetition of an earlier test in slightly changed circumstances, while the other two are original.
Sławomir Kalinowski
doaj