Results 41 to 50 of about 973,446 (295)

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Teoria de la eleccion racional: estructura conceptual y evolucion reciente.

Colombia Internacional, 2005
This article hopes to facilitate dialogue within political studies by presenting a general description of the conceptual structure of Rational Choice Theory, RCT.
Felipe Botero., Pablo Abitbol.
doaj  

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

A Portfolio Choice Problem in the Framework of Expected Utility Operators

Mathematics, 2019
Possibilistic risk theory starts from the hypothesis that risk is modeled by fuzzy numbers. In particular, in a possibilistic portfolio choice problem, the return of a risky asset will be a fuzzy number.
Irina Georgescu, Louis Aimé Fono
doaj   +1 more source

Closed-form portfolio optimization under GARCH models

Operations Research Perspectives, 2022
This paper develops an approximate closed-form optimal portfolio allocation formula for a spot asset whose variance follows a GARCH(1,1) process. We consider an investor with constant relative risk aversion (CRRA) utility who wants to maximize the ...
Marcos Escobar-Anel, Maximilian Gollart, Rudi Zagst   +2 more
doaj   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

Preferences for shifts in probabilities and expected utility theory

Estudios Económicos, 2007
Las preferencias definidas sobre loterías inducen preferencias sobre cambios en probabilidades. Definimos el axioma de independencia para preferencias definidas sobre cambios en probabilidades. Al usar esta versión del axioma de independencia construimos
David Cantalá
doaj  

Irrational Responses to Risk Preference Questionnaires by Patients with Diabetes with or without Retinopathy and Comparison with Those without Diabetes

Diabetes, Metabolic Syndrome and Obesity, 2020
Naoya Emoto,1,2 Akimi Soga,1 Izumi Fukuda,1 Kyoko Tanimura-Inagaki,1 Taro Harada,1 Hajime M Koyano,3 Rei Goto,4 Hitoshi Sugihara1 1Department of Endocrinology, Diabetes and Metabolism, Graduate School of Medicine, Nippon Medical School, Tokyo, Japan ...
Emoto N, Soga A, Fukuda I, Tanimura-Inagaki K, Harada T, Koyano HM, Goto R, Sugihara H   +7 more
doaj  

Risk, ambiguity and quantum decision theory

, 2007
In the present article we use the quantum formalism to describe the effects of risk and ambiguity in decision theory. The main idea is that the probabilities in the classic theory of expected utility are estimated probabilities, and thus do not follow ...
Aerts, Asano, Bagassi, Busemeyer, Cheng-Ming Jiang, Choustova, Croson, Hogarth, John C. Dunn, Khrennikov, Kühberger, Lambdin, Li, Li, Pothos, Savage, Shafir, Shafir, Shu Li, Tversky, Zuo-Jun Wang   +20 more
core   +1 more source

Neurobiological studies of risk assessment: A comparison of expected utility and mean-variance approaches [PDF]

, 2008
When modeling valuation under uncertainty, economists generally prefer expected utility because it has an axiomatic foundation, meaning that the resulting choices will satisfy a number of rationality requirements.
Bossaerts, Peter, d'Acremont, M.
core   +2 more sources