Results 51 to 60 of about 973,446 (295)
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Modeling the Relationship between Expected Gain and Expected Value
Asia Marketing Journal, 2016 Rational choice theory holds that the alternative with largest expected utility in the choice set should always be chosen. However, it is often observed that an alternative with the largest expected utility is not always chosen while the choice task ...
Eugene J. S. Won
doaj +1 more source
Coherent Diversification Measures in Portfolio Theory: An Axiomatic Foundation
Risks, 2022 We provide an axiomatic foundation for the measurement of correlation diversification in a one-period portfolio model. We propose a set of eight desirable axioms for this class of diversification measures.
Gilles Boevi Koumou, Georges Dionne
doaj +1 more source
Expected utility theory without the completeness axiom [PDF]
Journal of Economic Theory, 2004 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Dubra, Juan +2 more
openaire +4 more sources
Molecular Oncology, EarlyView.The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
Random Decisions as Rational Decisions
ProblemosRandom decision-making (RDM) is a method of choice in which an agent delegates the final selection to a random device (e.g., a coin). When faced with multiple options, RDM is often dismissed as an irrational approach. Even in symmetrical cases where RDM
Jianfei Shao
doaj +1 more source
Judging statistical models of individual decision making under risk using in- and out-of-sample criteria. [PDF]
PLoS ONE, 2014 Despite the fact that conceptual models of individual decision making under risk are deterministic, attempts to econometrically estimate risk preferences require some assumption about the stochastic nature of choice.
Andreas C Drichoutis, Jayson L Lusk
doaj +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Diversification Preferences in the Theory of Choice
, 2015 Diversification represents the idea of choosing variety over uniformity. Within the theory of choice, desirability of diversification is axiomatized as preference for a convex combination of choices that are equivalently ranked.
De Giorgi, Enrico G., Mahmoud, Ola
core +1 more source
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source