Results 81 to 90 of about 4,351,418 (319)
Targeted metabolomics reveals novel diagnostic biomarkers for colorectal cancer
Molecular Oncology, EarlyView.This study employed targeted metabolomic profiling to identify 302 distinct metabolites present in platelet‐rich plasma (PRP), revealing aberrant metabolic profiles amongst individuals diagnosed with colorectal cancer (CRC). Compared to carcinoembryonic antigen (CEA) and cancer antigen 19‐9 (CA199), our metabolite panel showed improved sensitivity ...
Zuojian Hu +7 more
wiley +1 more source
Q fever outbreak in the terraced vineyards of Lavaux, Switzerland
New Microbes and New Infections, EarlyView., 2014 Abstract Coxiella burnetii infection (Q fever) is a widespread zoonosis with low endemicity in Switzerland, therefore no mandatory public report was required. A cluster of initially ten human cases of acute Q fever infections characterized by prolonged fever, asthenia and mild hepatitis occurred in 2012 in the terraced vineyard of Lavaux ...
C. Bellini +9 more
wiley +1 more source
Treatment planning with a 2.5 MV photon beam for radiation therapy
Journal of Applied Clinical Medical Physics, Volume 23, Issue 12, December 2022., 2022 Abstract Purpose The shallow depth of maximum dose and higher dose fall‐off gradient of a 2.5 MV beam along the central axis that is available for imaging on linear accelerators is investigated for treatment of shallow tumors and sparing the organs at risk (OARs) beyond it.
Navid Khaledi +5 more
wiley +1 more source
, 2021 Christina West widmet sich in diesem Beitrag der Rolle von Experimenten bei der Wissensproduktion, insbesondere in transdisziplinären Forschungs- und Lehrkontexten. Nach einer allgemeinen Begriffsbestimmung fokussiert sie auf transdisziplinäre Experimente in engerem Sinne, die insbesondere in den transformativen Wissenschaften und in der ...
openaire +1 more source
Democratizing Children's Computation: Learning Computational Science as Aesthetic Experience [PDF]
arXiv, 2015 In this paper, we argue that a democratic approach to children's computing education in a science class must focus on the aesthetics of children's experience. In Democracy and Education, Dewey links "democracy" with a distinctive understanding of "experience". For Dewey, the value of educational experiences lies in "the unity or integrity of experience"
arxiv
KMT2A degradation is observed in decitabine‐responsive acute lymphoblastic leukemia cells
Molecular Oncology, EarlyView.We demonstrate that decitabine (DEC) not only degrades the DNA methyltransferase DNMT1 but also the leukemic driver lysine methyltransferase KMT2A likely due to structural similarity of the DNA‐binding CXXC domains. DEC influences KMT2A downstream processes and synergizes with menin inhibitor revumenib (REV) to decrease leukemic cell proliferation, and
Luisa Brock +10 more
wiley +1 more source
Impact of flexible noise control (FNC) image processing parameters on portable chest radiography
Journal of Applied Clinical Medical Physics, Volume 23, Issue 12, December 2022., 2022 Abstract There is a lack of understanding in the performance of flexible noise control (FNC) processing, which is used in digital radiography on a scanner vendor and has four parameters each involving multiple options. The aim of this study was to investigate the impact of FNC on portable chest imaging. An anthropomorphic chest phantom was imaged using
Krystal M. Kirby +6 more
wiley +1 more source
Revisiting Prioritized Experience Replay: A Value Perspective [PDF]
arXiv, 2021 Experience replay enables off-policy reinforcement learning (RL) agents to utilize past experiences to maximize the cumulative reward. Prioritized experience replay that weighs experiences by the magnitude of their temporal-difference error ($|\text{TD}|$) significantly improves the learning efficiency.
arxiv
Molecular Oncology, EarlyView.CD226+CD8+ T cells express elevated levels of RUNX2, exhibit higher proliferation capacity, cytokines and cytolytic molecules expression, and migratory capacity. In contrast, CD226−CD8+ T cells display an exhausted phenotype associated with the increased expression of co‐inhibitory receptors and impaired effector functions.
Maryam Rezaeifar +4 more
wiley +1 more source
Journal of Applied Clinical Medical Physics, Volume 23, Issue 12, December 2022., 2022 Abstract This study aimed to evaluate the clinical beam commissioning results and lateral penumbra characteristics of our new pencil beam scanning (PBS) proton therapy using a multi‐leaf collimator (MLC) calculated by use of a commercial Monte Carlo dose engine.
Yuki Tominaga +5 more
wiley +1 more source