Results 101 to 110 of about 704,399 (283)

Rethinking airport passenger experience. An interdisciplinary service + spatial design approach

open access: yes, 2020
LAUREA MAGISTRALEC'è una crescente domanda di ripensare l'esperienza dei passeggeri nel settore dell'aviazione dall'ultimo decennio. L'automazione dei processi, i checkpoint self-service e la trasformazione digitale stanno cambiando il modo in cui gli ...
Modi, Pooja Parag
core  

Co-designing complex therapy interventions with parents as partners in the care of children with cerebral palsy: An Experience-based Co-design study in England

open access: yesResearch in Developmental Disabilities
Parents of children with hemiplegic cerebral palsy are increasingly involved in therapy intervention delivery. Enhancing the ways that parents are supported in delivery is key to optimising outcomes. This study aimed to refine an existing programme in England to better support parents partnering in their child's intervention delivery.Experience-based ...
Massey, Jill   +4 more
openaire   +3 more sources

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

open access: yesFEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin   +3 more
wiley   +1 more source

Time‐restricted feeding prior to Mycobacterium tuberculosis infection reduces tissue CD4+ T cells with limited impact on bacterial clearance

open access: yesFEBS Open Bio, EarlyView.
Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta   +7 more
wiley   +1 more source

Towards a kansei-based user modeling methodology for eco-design [PDF]

open access: yes, 2013
We propose here to highlight the benefits of building a framework linking Kansei Design (KD), User Centered Design (UCD) and Eco-design, as the correlation between these fields is barely explored in research at the current time.
AOUSSAT, Améziane   +2 more
core  

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

open access: yesFEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin   +12 more
wiley   +1 more source

Interactive design principles : online communities and the user experience\ud

open access: yes, 2007
This paper identifies interactive design principles through user experience via online communities that will allow web site designers to create compelling, useful and truly interactive user experiences. There are many features of online communities that
Park, Ji Yong
core  

Co-design: Do we need to (co-)change our (co-)thinking? (Editorial)

open access: yes
The origin of co-design is first traced back to the ‘northern’ and ‘southern’ traditions of participatory research. The ‘northern’ tradition of Kurt Lewin (1948) promoted empowerment and social equity through action cycles as means of work that was ‘with’
McShane, M, Gustafsson, L
core   +1 more source

Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1

open access: yesFEBS Open Bio, EarlyView.
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay   +2 more
wiley   +1 more source

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