Results 61 to 70 of about 704,399 (283)

Co-design and evaluation of an information and communication technology-based solution to support mild stroke – an experience-based co-design study

open access: yesDisability and Rehabilitation: Assistive Technology
Approximately 60-70% of people with stroke experience a mild incident. However, mild stroke can significantly impact daily life for these individuals and their significant others. Reviews suggest that the use of information and communication technology (ICT) can add value to the existing stroke rehabilitation. The purpose of the current study was to co-
Stina Meyer Larsen   +3 more
openaire   +2 more sources

Integrating student and teacher insights to a school-based alcohol program through co-design

open access: yes, 2021
School-based programs may be more effective when an array of stakeholders, including users, are involved during the relevant stages of program co-creation-specifically during key development stages such as design, implementation and evaluation.
Durl, James   +3 more
core   +1 more source

Development of a peer support model using experience-based co-design to improve critical care recovery [PDF]

open access: yes, 2019
Objectives: To use experience-based co-design to identify the key design requirements of a peer support model for critical care survivors; understand the use of the experience-based co-design method from clinician, patients, and family perspectives ...
Belinda MacLeod-Smith (13463592)   +14 more
core   +2 more sources

Showcasing patient and public involvement: Using consultation, collaboration and co-design to shape a respiratory programme

open access: yesPatient Experience Journal, 2022
The NHS is committed to working with patient groups and the public to co-design health services to ensure that lived experience is used to optimise service design and delivery.
Kate Strong   +2 more
doaj  

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Patient Experience Journal Awards: Celebrating our 2019 Recipients

open access: yesPatient Experience Journal, 2020
In association with The Beryl Institute, Patient Experience Journal introduced the inaugural Patient Experience Journal (PXJ) Awards. The annual awards celebrate important contributions to the literature and articles of impact in research and practice ...
Patient Experience Journal
doaj  

Giving voice to equitable collaboration in participatory design [PDF]

open access: yes, 2007
An AHRC funded research project titled Experimenting with the Co-experience Environment (June 2005 – June 2006) culminated in a physical environment designed in resonance with a small group of participants.
O'Connor, Mark   +13 more
core  

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

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