Results 131 to 140 of about 13,984,903 (297)

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

The Malaysian Experience

open access: yes, 2019
The Malaysian story involves a farsighted leadership that has mobilized the considerable assets of a resource-rich country to translate a long-term vision of nation building into action and transformational
World Bank Group
core   +1 more source

Health education with hypertensive illiterates: experience report

open access: yesRevista de Enfermagem da UFPI, 2020
DOI: https://doi.org/10.26694/2238-7234.8esp77-80 Objetivo: relatar a experiência de ação educativa em saúde junto a um grupo de idosos analfabetos com níveis pressóricos variantes.
Lívia Augusta César da Silva Pereira, Claudete Ferreira de Souza Monteiro, Maria da Conceição de Souza Melo, Isabelly Cristina Honorato de Queiroz
doaj  

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

Changing Myths Into Truths: Dispelling Physician Misconceptions on Patient Experience

open access: yes
Patient experience work can be viewed by some physicians as outside their scope of practice and therefore the responsibility of non-medical providers. Assumptions may also be made by providers about what patient experience work is and is not. These myths
Kanter, Michael H   +15 more
core   +1 more source

Leistungsorientierte Mittelvergabe an der Medizinischen Hochschule Hannover: Praxisbericht der Bibliothek / Performance-related bonuses at Hannover Medical School: practical experience report of the library

open access: yesGMS Medizin – Bibliothek – Information, 2011
Since 2008 the Library of the Hannover Medical School collects and execute the publication data of the scientific staff for calculation of “performance-related bonuses” in the array publications.
Schmiel, Markus
doaj  

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

Mastering the Art of Listening: The Human Experience Superpower [PDF]

open access: yes
As human beings we do not live in isolation. Our existence is framed in the context of others. We are a part of families and teams, communities and countries; all which provide us with ideas and information, most delivered through the interactions we ...
Wolf, Jason A.
core   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach   +9 more
wiley   +1 more source

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