Results 121 to 130 of about 9,267,633 (320)

Experiment definition phase shuttle laboratory LDRL-10.6 experiment [PDF]

The 10.6 microns laser data relay link (LDRL 10.6) program was directed to applying optical communications to NASA's wideband data transmission requirements through the 1980's.

core   +1 more source

Cell density–dependent nuclear‐cytoplasmic shuttling of SETDB1 integrates with Hippo signaling to regulate YAP1‐mediated transcription

FEBS Letters, EarlyView.
At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom, Jaewoong Jang, Jung Sun Park, Yong‐Kook Kang   +3 more
wiley   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Solar array flight experiment/dynamic augmentation experiment [PDF]

This report presents the objectives, design, testing, and data analyses of the Solar Array Flight Experiment/Dynamic Augmentation Experiment (SAFE/DAE) that was tested aboard Shuttle in September 1984.
Pack, Homer C., Jr., Young, Leighton E.
core   +1 more source

Understanding car sharing preferences and mode substitution patterns: A stated preference experiment

, 2020
Andrea Papu Carrone, Valerie Maria Hoening, Anders Fjendbo Jensen, Stefan Lindhard Mabit, Jeppe Rich   +4 more
openalex   +2 more sources

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón   +8 more
wiley   +1 more source

The TOTEM Experiment at LHC

, 2008
The TOTEM experiment at the CERN LHC is here presented. After an overview of the experimental apparatus, the measurement of the total pp cross section, elastic scattering and diffractive phenomena is described.
Latino, Giuseppe
core  

Impact of habitat management on grey partridge populations: assessing wildlife cover using a multisite BACI experiment [PDF]

, 2004
Elisabeth Bro, P. Mayot, Eve Corda, F. Reitz   +3 more
openalex   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source

Moving Toward Collecting High-Quality Umbilical Cord Blood: Application of Quality Control Circle

Journal of Blood Medicine
Jun Peng,1,2,* Cong-Ying Shi,3,* Fa-Ying Kuang,2 Tian-Bao Ma,3 Xi-Bao Yu3 1Department of Gynecology and Obstetrics, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong, People’s Republic of China; 2Department of Gynecology
Peng J, Shi CY, Kuang FY, Ma TB, Yu XB
doaj