Results 41 to 50 of about 4,461,495 (296)

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Experimenting with a Design Experiment.

open access: yesRevista internacional de sociologia, 2011
The design experiment is an experimental research method that aims to help design and further develop new (policy) instruments. For the development of a set of guidelines for the facilitation of citizens’ initiatives by local governments, we are experimenting with this method.
Bakker, Judith   +1 more
openaire   +2 more sources

EXPERIMENTS [PDF]

open access: yesSchool Science and Mathematics, 1914
n ...
openaire   +2 more sources

Report of the Guam Agricultural Experiment Station. [PDF]

open access: yes, 1915
Mode of access: Internet.Continued by: Annual report (Guam Agricultural Experiment Station)Continues: Guam Agricultural Experiment Station. Annual report of the Guam Agricultural Experiment Station for .
Guam Agricultural Experiment Station.
core  

Epigallocatechin gallate attenuated high glucose-induced pancreatic beta cell dysfunction by modulating DRP1-mediated mitochondrial apoptosis pathways

open access: yesScientific Reports
Long-term exposure to hyperglycemic conditions leads to β-cell dysfunction, particularly mitochondrial dysfunction, and inflammatory and oxidative stress responses, which are considered the primary causes of β-cell death and the hallmarks of diabetes ...
Xu Jia   +11 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Visual and fluorescent detection of Moraxella catarrhalis by multiple cross displacement amplification-based assay

open access: yesHeliyon
Moraxella catarrhalis (M. catarrhalis), once considered as a harmless commensal bacterium, is now recognized as a significant pathogen associated with human mucosal infection.
Xiaolan Huang   +11 more
doaj   +1 more source

In vitro evaluation of fungal antagonists of Phytophthora nicotianae

open access: yesPlant Protection Science, 2002
As tobacco black shank epidemics caused by Phytophthora nicotianae occurred in central Italy in the late 1990s, fungal antagonists of the pathogen were searched in the rhizosphere of tobacco plants.
R. Nicoletti, F. Raimo, E. Cozzolino
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

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