Results 41 to 50 of about 5,187,758 (262)
Experimenting with a Design Experiment.
Revista internacional de sociologia, 2011 The design experiment is an experimental research method that aims to help design and further develop new (policy) instruments. For the development of a set of guidelines for the facilitation of citizens’ initiatives by local governments, we are experimenting with this method.
Bakker, Judith +1 more
openaire +2 more sources
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Scientific ReportsLong-term exposure to hyperglycemic conditions leads to β-cell dysfunction, particularly mitochondrial dysfunction, and inflammatory and oxidative stress responses, which are considered the primary causes of β-cell death and the hallmarks of diabetes ...
Xu Jia +11 more
doaj +1 more source
HeliyonMoraxella catarrhalis (M. catarrhalis), once considered as a harmless commensal bacterium, is now recognized as a significant pathogen associated with human mucosal infection.
Xiaolan Huang +11 more
doaj +1 more source
In vitro evaluation of fungal antagonists of Phytophthora nicotianae
Plant Protection Science, 2002 As tobacco black shank epidemics caused by Phytophthora nicotianae occurred in central Italy in the late 1990s, fungal antagonists of the pathogen were searched in the rhizosphere of tobacco plants.
R. Nicoletti, F. Raimo, E. Cozzolino
doaj +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
, 2021 Christina West widmet sich in diesem Beitrag der Rolle von Experimenten bei der Wissensproduktion, insbesondere in transdisziplinären Forschungs- und Lehrkontexten. Nach einer allgemeinen Begriffsbestimmung fokussiert sie auf transdisziplinäre Experimente in engerem Sinne, die insbesondere in den transformativen Wissenschaften und in der ...
openaire +1 more source
Crowdsourcing Quality of Experience Experiments [PDF]
, 2017 Crowdsourcing enables new possibilities for QoE evaluation by moving the evaluation task from the traditional laboratory environment into the Internet, allowing researchers to easily access a global pool of workers for the evaluation task. This makes it not only possible to include a more diverse population and real-life environments into the ...
Sebastian Egger-Lampl +7 more
openaire +4 more sources