Results 61 to 70 of about 2,743,368 (242)

In situ Adsorption Technology for Remediation of Cr(Ⅵ) Contaminated Soil

Yankuang ceshi
The commonly used remediation technologies for Cr(Ⅵ) contaminated soil, such as guest soil, reduction, solidification, microbiology, etc., have drawbacks such as high cost, slow efficiency, and secondary oxidation of Cr(Ⅵ).
Zhaoxin ZHANG, Ningning CAO, Linji LI, Suqing LIU, Jiahao LI, Cui CAO, Heping LI, Kai ZHANG, Yongli SHI   +8 more
doaj   +1 more source

The Biosynthesis of Heterophyllin B in Pseudostellaria heterophylla From prePhHB-Encoded Precursor

Frontiers in Plant Science, 2019
Plant cyclic peptides (CPs) are a large group of small molecule metabolites found in a wide variety of plants, including traditional Chinese medicinal plants.
Wei Zheng, Wei Zheng, Tao Zhou, Jun Li, Weike Jiang, Jinqiang Zhang, Chenghong Xiao, Dequn Wei, Changgui Yang, Rong Xu, Anhui Gong, Chen Zhang, Yan Bi   +12 more
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Evaluation of eight repellents in deterring eastern cottontail herbivory in Connecticut

Human-Wildlife Interactions, 2017
Herbivory by eastern cottontails (Sylvilagus floridanus) can be the source of significant agricultural, nursery, and managed landscape damage. Where cottontails cannot be managed by lethal means or where trap and release is infeasible, repellents may be ...
Scott C. Williams, Michael R. Short
doaj   +1 more source

Educational Experiences and Experience Styles

Interaction Design and Architecture(s), 2010
The on-going revival of educational processes as experiences leads to a complex reflection on the characteristics that can make such processes more meaningful, especially on a personal level. In this article we propose a cultural framework that, starting from the definition of a set of general features characterizing the ‘experience’, allows to ...
GIOVANNELLA, CARLO, Spadavecchia, C, Camusi, A.   +2 more
openaire   +3 more sources

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Deciphering the Pharmacological Mechanism of the Herb Radix Ophiopogonis in the Treatment of Nasopharyngeal Carcinoma by Integrating iTRAQ-Coupled 2-D LC-MS/MS Analysis and Network Investigation

Frontiers in Pharmacology, 2019
The herb Radix Ophiopogonis (RO) has been used effectively to treat nasopharyngeal carcinoma (NPC) as an adjunctive therapy. Due to the complexity of the traditional Chinese herbs, the pharmacological mechanism of RO’s action on NPC remains unclear.
Xuesong Feng, Hailong Shi, Xu Chao, Fei Zhao, Liang Song, Minhui Wei, Hong Zhang, Hong Zhang   +7 more
doaj   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Experiments, thought experiments and virtual experiments

, 2011
Bibliography: p.
openaire   +2 more sources

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source