Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
Effect of Argon Injection into the Down-Leg of RH on the Inclusion Removal in Industrial Trials. [PDF]
Materials (Basel)Pan Y +5 more
europepmc +1 more source
Quadratic Sagnac effect — the influence of the gravitational potential of the Coriolis force on the phase difference between the arms of a rotating Michelson interferometer (an explanation of D C Miller's experimental results 1921—1926) [PDF]
, 2015 G. B. Malykin, V. I. Pozdnyakova
openalex +1 more source
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Experimental and Numerical Analysis of Sandwich Structures. [PDF]
Materials (Basel)Pozorski Z, Lange J, Sabik A.
europepmc +1 more source
Experimental study of a vortex in a magnetic field
, 2002 Binod Sreenivasan, Thierry Alboussière
openalex +2 more sources
The Investigation on the Effect of the Vegetal Origin Ankaferd Blood Stopper in Experimental Intra-Abdominal Surgery Over Rabbits [PDF]
, 2010 Erkan Duz . +6 more
openalex +1 more source
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Host heterogeneity and unpredictability in parasite outbreaks. [PDF]
Proc Natl Acad Sci U S ACohen JA, Viney M, Fenton A.
europepmc +1 more source
Direct Observation of Inward Electron Flux Being Blocked in the Large Helical Device [PDF]
Experimental Group" LHD, K. "Narihara
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