Results 121 to 130 of about 4,825,097 (315)
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
Applied SciencesThis paper presents an experimental analysis of a high-response piezoelectric actuator system for the modular design of hydraulic digital fluid control units.
Marko Šimic, Niko Herakovič
doaj +1 more source
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Nonlinear experimental analysis of complex dynamics in structural systems
, 2011 An overview of the nonlinear experimental analysis of complex dynamics in structural systems is presented. General issues concerned with detection and classification of regular and complex dynamics are addresses, focusing on the reconstruction of ...
REGA, GIUSEPPE
core
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
Nihon Kikai Gakkai ronbunshuThis paper aims to clarify the behavior and damage conditions of batteries when multi-rotor unmanned aerial vehicles (drones) in horizontal flight collide with a structure to obtain the engineering knowledge that serves to consider the method of the ...
Kengo TAKAHASHI +3 more
doaj +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
FEBS Letters, EarlyView.Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
Experimental Investigation of Fatigue of Thin-Walled Welded Structures of Commercial Vehicle Frames
The Annals of “Dunarea de Jos” University of Galati. Fascicle IX, Metallurgy and Materials Science, 2007 The fatigue behavior of bus frame components consisting of thin-walled tube beams joined together by fillet welding has been investigated. Numerical analysis by means of finite elements and experimental stress analysis by means of strain gages explored ...
Athanassios FOKILIDIS, Georgios SAVAIDIS
doaj
MetalsThis study investigates a heavy-duty CNC machine tool crossbeam casting manufactured by a leading heavy machine tool producer. A numerical simulation model for the demolding process was developed using proprietary Computer-Aided Engineering (CAE ...
Jingfan Cheng, Yiqi Zhang, Dunming Liao
doaj +1 more source