Results 161 to 170 of about 30,538,029 (314)

Integrated Bioinformatic and Experimental Analysis of PTEN and DNMT1 Regulation in NSCLC. [PDF]

Biomedicines
El Nobey MA, Shaikh Omar AM, Batawi AH, Alharthi A, Althubaiti EH, Alghamdi MA, Altalhi SA, Bakhsh T, Al Aamri ZM.   +8 more
europepmc   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Integrative transcriptomic and experimental analysis identifies GREM1 as a pro-metastatic mediator in lung adenocarcinoma. [PDF]

J Transl Med
Li ZQ, Huang HR, Zhai KR, Li B.
europepmc   +1 more source

Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers

FEBS Letters, EarlyView.
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui, Agnes Banreti, Armelle L. Ernst, Guillaume Leseigneur, Uwe J. Meierhenrich   +4 more
wiley   +1 more source

Standing work and low back pain: An experimental analysis of risk factors. [PDF]

Work
Osorio-Vasco J, Rojas-Mora J, Barrera-Causil C, Rodríguez Y.   +3 more
europepmc   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

FEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil, Jeffrey A. Hawkes, Cecilia Blikstad, Pia Lindberg   +3 more
wiley   +1 more source

Bioinformatics and experimental analysis identify CHN2 and MEF2C as diagnostic biomarkers for tuberculosis. [PDF]

Am J Transl Res
Wu J, Wen Y, Huang S.
europepmc   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

FEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux, Christian Lévêque, Fodil Azzaz, Marion Sangiardi, Sarosh R Irani, Michael Seagar, Jacques Fantini, Oussama El Far   +7 more
wiley   +1 more source

Experimental analysis of flash flood-induced scour on semi-arid hillslopes. [PDF]

Sci Rep
Rostamzadeh E, Madadi MR, Zounemat-Kermani M.   +2 more
europepmc   +1 more source

THE ANALYSIS OF SELECTION IN EXPERIMENTAL POPULATIONS [PDF]

Genetics, 1968
W H, DuMouchel, W W, Anderson
openaire   +2 more sources