Results 101 to 110 of about 6,178,835 (292)

Prevention of arthritis by interleukin 10-producing B cells [PDF]

, 2003
In this study we have shown that activation of arthritogenic splenocytes with antigen and agonistic anti-CD40 gives raise to a B cell population that produce high levels of interleukin (IL)-10 and low levels of interferon (IFN)-{gamma}. Transfer of these
Mauri, C., Mushtaq, N., Marco Londei, Claudia Mauri, Naseem Mushtaq, Gray, D., Londei, M., David Gray   +7 more
core   +1 more source

Septic arthritis: immunopathogenesis, experimental models and therapy

Journal of Venomous Animals and Toxins including Tropical Diseases, 2014
Septic arthritis is an inflammatory disease of the joints that is started by an infection whose most common agent is Staphylococcus aureus. In this review we discuss some of the most arthritogenic bacterial factors and the contribution of innate and ...
Priscila Maria Colavite, Alexandrina Sartori   +1 more
doaj   +1 more source

Distinct Systemic Sclerosis Phenotypes Related to Ethnicity: An Opportunity to Personalize Care?

Arthritis Care &Research, EarlyView.
Objective The objective is to describe and compare demographic, clinical, and serological characteristics of patients with systemic sclerosis (SSc) according to ethnic background. Methods Participants enrolled in the Canadian Scleroderma Research Group cohort who self‐identified to a single ethnicity group were included.
Danick Goulet, Camille Guertin, Maggie Larché, Isabelle Ferdinand, Marie Hudson, May Y. Choi, Mohammed Osman, Janet Pope, Carter Thorne, Murray Baron, Sasha Bernatsky, Sabrina Hoa   +11 more
wiley   +1 more source

Association of the IL-10 gene family locus on chromosome 1 with juvenile idiopathic arthritis (JIA) [PDF]

, 2012
The cytokine IL-10 and its family members have been implicated in autoimmune diseases and we have previously reported that genetic variants in IL-10 were associated with a rare group of diseases called juvenile idiopathic arthritis (JIA). The aim of this
Bryant, A., Ursu, S., Ursu Simona, Hinks, A, Forabosco, P, Omoyinmi, E, Ebun Omoyinmi, Hamaoui, Raja, Hinks, A., Woo, P., Ebun Omoyinmi (125984), Simona Ursu (125994), Forabosco, Paola, Wendy Thomson (68038), Lewis Cathryn M., Childhood Arthritis Response to Medication Study (CHARMS), Omoyinmi, Ebun, Lucy R. Wedderburn (125999), Thomson, W, Cathryn M Lewis, Lewis, Cathryn M; id_orcid, Forabosco Paola, Raja Hamaoui, Ursu, S, Wedderburn, L.R., Wedderburn, Lucy R., Ursu, Simona, Annette Bryant, Omoyinmi Ebun, Wedderburn, LR, ?, ?, Hamaoui Raja, Hamaoui, R., Hinks Anne, Patricia Woo, Annette Bryant (125990), Wedderburn, Lucy R, Bryant, Annette, Woo, P, Lewis, C.M., Lewis, CM, Woo, Patricia, Bryant, A, Forabosco, P., Patricia Woo (60657), Gardner-Medwin, J., Lewis, Cathryn M., Raja Hamaoui (125988), Wedderburn Lucy R., Hamaoui, R, Lucy R Wedderburn, Hinks, Anne, Cathryn M. Lewis (126002), Paola Forabosco, Anne Hinks, Omoyinmi, E., BSPAR study group, Thomson, W., Thomson Wendy, Paola Forabosco (125986), Wendy Thomson, Thomson, Wendy, Woo Patricia, Anne Hinks (23498), Bryant Annette, Simona Ursu, Childhood Arthritis Prospective Study (CAPS)   +66 more
core   +1 more source

Real‐World Safety and Effectiveness of JAK Inhibitors in Systemic Sclerosis: A Propensity‐Matched Study From the EUSTAR Cohort

Arthritis Care &Research, EarlyView.
Objective JAK inhibitors (JAKi) have shown promising effects in early‐phase studies of systemic sclerosis (SSc). We aimed to assess the safety and explore the effectiveness of JAKi compared to conventional immunosuppressants in SSc. Methods A longitudinal retrospective study of the European Scleroderma Trials and Research Group (EUSTAR) cohort was ...
Stefano Di Donato, Marie‐Elise Truchetet, Marco Minerba, Oliver Distler, Juan José Alegre Sancho, Yolanda Braun‐Moscovici, Christina Bergmann, Petros Sfikakis, Jeska K. de Vries‐Bouwstra, Murray Baron, Silvia Bellando‐Randone, Lorenzo Dagna, Christopher P. Denton, Madelon C. Vonk, Vanessa Smith, Ivan Castellvi, Gabriela Riemekasten, Andra Balanescu, Masataka Kuwana, Maria De Santis, Kamal Solanki, Anastas Batalov, Vahan Mukuchyan, Marco Matucci‐Cerinic, Yannick Allanore, Francesco Del Galdo, Michael Hughes, EUSTAR Collaborators   +27 more
wiley   +1 more source

joiNTed : the Arthritis & Osteoporosis Northern Territory newsletter

, 2008
This publication contains may contain links to external sites. These external sites may no longer be active.Trading as Arthritis & Osteoporosis NTMade available by the Northern Territory Library via the Publications (Legal Deposit) Act 2004 (NT).This ...
Arthritis & Osteoporosis NT
core  

The clinical features and surgical treatment of acute septic arthritis in Malawian children. [PDF]

, 2006
Introduction: Untreated and poorly treated septic arthritis in children is a major cause of orthopaedic pathology in Malawi and the rest of sub Saharan Africa, yet little has been published on its early treatment, or its incidence, clinical features and ...
Lavy, C.B.D.
core  

Animal models of rheumatoid pain: experimental systems and insights

Arthritis Research & Therapy, 2017
Severe chronic pain is one of the hallmarks and most debilitating manifestations of inflammatory arthritis. It represents a significant problem in the clinical management of patients with common chronic inflammatory joint conditions such as rheumatoid ...
Bradford D. Fischer, Adeshina Adeyemo, Michael E. O’Leary, Andrea Bottaro   +3 more
doaj   +1 more source

Anorectal Dysfunction in Systemic Sclerosis: Clinical Phenotypes and Functional Patterns

Arthritis Care &Research, EarlyView.
Objective The aim of this study was to characterize specific physiologic defects in anorectal dysfunction in systemic sclerosis (SSc) using anorectal manometry (ARM), evaluate associations with gastrointestinal (GI) and extraintestinal clinical phenotypes, and explore potential serologic markers for risk stratification.
Timothy Kaniecki, Alireza Amindarolzarbi, Tsion Abdi, John Clarke, Michael Hughes, Ami A. Shah, Zsuzsanna H. McMahan   +6 more
wiley   +1 more source

Frailty Predicts Incident Osteoporotic Fractures in Veterans with Rheumatoid Arthritis

Arthritis Care &Research, EarlyView.
Objective Rheumatoid arthritis (RA) is associated with an increased risk of frailty and osteoporosis, but the relationship between frailty and incident osteoporotic fractures in RA is underexplored. Methods Data were from the Veterans Affairs (VA) Rheumatoid Arthritis Registry. Frailty was measured using the VA Frailty Index (VAFI).
Katherine D. Wysham, Hannah F. Brubeck, Aaron Baraff, Punyasha Roul, Namrata Singh, James S. Andrews, Grant W. Cannon, Gary A. Kunkel, Ted R. Mikuls, Bryant R. England, Dolores M. Shoback, Patricia P. Katz, Jose M. Garcia, Ariela R. Orkaby, Joshua F. Baker   +14 more
wiley   +1 more source