Results 181 to 190 of about 6,178,835 (292)

Evidence for Pro-Inflammatory Activity of LTα3 on Macrophages: Significance for Experimental Arthritis and for Therapeutic Switching in Rheumatoid Arthritis Patients. [PDF]

Int J Mol Sci
Benezech A, Gottenberg JE, Degboé Y, Kruglov A, Grogan J, Briand-Mésange F, Cantagrel A, Ruyssen-Witrand A, Davignon JL.   +8 more
europepmc   +1 more source

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source

Inhibition of GRK2-PDE4D Axis Suppresses Fibroblast-Like Synoviocytes Hyperplasia and Alleviates Experimental Arthritis. [PDF]

Int J Biol Sci
Han D, Sun H, Zhang R, Ge H, Guo P, Chu R, Fang R, Han Y, He S, Li R, Tu J, Wei W, Ma Y, Wang Q.   +13 more
europepmc   +1 more source

Tofacitinib treatment alters mucosal immunity and gut microbiota during experimental arthritis. [PDF]

Clin Transl Med, 2020
Hablot J, Ferhat M, Lavelle A, Salem F, Taieb M, Medvedovic J, Kindt N, Reboul P, Cailotto F, Jouzeau JY, Eberl G, Sokol H, Moulin D.   +12 more
europepmc   +1 more source

Qing-Luo-Yin Alleviated Experimental Arthritis in Rats by Disrupting Immune Feedback Between Inflammatory T Cells and Monocytes: Key Evidences from Its Effects on Immune Cell Phenotypes. [PDF]

J Inflamm Res, 2021
Wang DD, Wu XY, Dong JY, Cheng XP, Gu SF, Olatunji OJ, Li Y, Zuo J.   +7 more
europepmc   +1 more source

An Aggregation‐Induced Polymerization Poly(Disulfide)‐Drug Nanoplatform for Autoimmune Uveitis Therapy via Inhibiting the cGAS‐STING Pathway

Advanced Science, EarlyView.
A cationic poly(disulfide)‐drug nanoplatform (LA/DexP) was developed to treat experimental autoimmune uveitis (EAU). With potent blood‐retinal barrier penetrability, LA/DexP releases DSP in response to high ROS and scavenges cfDNA to inhibit the cGAS‐STING signaling pathway.
Yuelan Wu, Wenbo Geng, Qinjin Dai, Wanyun Zhang, Yuxian Lai, Pei Zhang, Chunjiang Zhou, Yinuo Wang, Qingfeng Cao, Xiang Luo, Yujie Lai, Changwei Huang, Peizeng Yang   +12 more
wiley   +1 more source

Don't sit still for arthritis pain

Black and white poster showing a woman standing beside a bike with a brick road in the background. The poster explains that 30 minutes of physical activity three days a week can help combat the pain of arthritis. Going for a walk, riding a bike, dancing,

core  

The HRAS-binding C2 domain of PLCη2 suppresses tumor-like synoviocytes and experimental arthritis in rheumatoid arthritis. [PDF]

Exp Mol Med
Jeon HM, Noh HS, Jeon MG, Park JH, Lee YS, Seo G, Cheon YH, Kim M, Han MK, Park JY, Lee SI.   +10 more
europepmc   +1 more source

A Monolithic Janus Hydrogel Pressure Sensor for Wearable Motion and Physiological Monitoring

Advanced Science, EarlyView.
This work reports a monolithic Janus hydrogel pressure sensor featuring integrated conductive PEDOT and insulating PEGDA layers. The fabricated device achieves a rapid response time, a wide operating range, and good cyclic durability. The sensor demonstrates robust performance in tracking dynamic human joint motions, offering a scalable strategy for ...
Syed Atif Ali, Zeeshan Alam Ansari, Reynaldo Carlos Kuizon Montalbo, Hailemichael Ayalew, Yu‐Sheng Hsiao, Chih‐Wei Chu, Hsiao‐hua Yu, Hsiung‐Lin Tu   +7 more
wiley   +1 more source

Systemic and local antiinflammatory effect of magnesium chloride in experimental arthritis. [PDF]

Adv Rheumatol
Pinto ACMD, de Melo Nunes R, de Freitas Carvalho WV, Girão VCC, Rocha FAC.   +4 more
europepmc   +1 more source