Results 151 to 160 of about 8,299,755 (321)

Chemotherapy plus bevacizumab with or without anti-programmed death 1 immunotherapy as the second-line therapy in colorectal cancer. [PDF]

World J Gastroenterol
Gao Z, Wang XY, Shen ZG, Liu JH, Wang XY, Wu SK, Jin X.   +6 more
europepmc   +1 more source

Experimental studies of a cisplatin delivery system for local chemotherapy of malignant diseases

, 1990
Osamu Ike, Yasuhiko Shimizu, Ryoichi Wada, Norihito Okumura, Song-Hyu Hyon, Satoshi Watanabe, Yoshito Ikada   +6 more
openalex   +2 more sources

3D Bioprinted Head and Neck Squamous Cell Carcinoma (HNSCC) Model Using Tunicate Derived Nanocellulose (NC) Bioink

Advanced Healthcare Materials, Volume 14, Issue 7, March 14, 2025.
A 3D bioprinted HNSCC model for use in anti‐cancer drug testing is established in proof‐of‐concept. The innovative tunicate‐derived nanocellulose hydrogel proved to be a viable alternative to gelatin‐based hydrogel, offering improved bioprintability for HNSCC model establishment.
Alexya Azhakesan, Johann Kern, Ankit Mishra, Christine Selhuber‐Unkel, Annette Affolter, Paul Gatenholm, Nicole Rotter, Karen Bieback   +7 more
wiley   +1 more source

Randomized Phase III Study of EGFR Tyrosine Kinase Inhibitor and Intercalated Platinum-Doublet Chemotherapy for Non-Small Cell Lung Cancer Harboring EGFR Mutation. [PDF]

Clin Cancer Res
Kanda S, Niho S, Kurata T, Nomura S, Kawashima Y, Iwama E, Yokoyama T, Watanabe Y, Tanaka H, Fujiwara Y, Zenke Y, Azuma K, Taniguchi H, Toyozawa R, Hosomi Y, Murakami H, Hara S, Bessho A, Yamamoto N, Ohe Y.   +19 more
europepmc   +1 more source

Targeted chemotherapy with cytotoxic bombesin analogue AN‐215 inhibits growth of experimental human prostate cancers [PDF]

, 2005
Anton Stangelberger, Andrew V. Schally, Markus Letsch, Károly Szepesházi, Attila Nagy, Gábor Halmos, Célia A. Kanashiro, Eva Corey, Robert L. Vessella   +8 more
openalex   +1 more source

“Therapies Through Gut:” Targeted Drug Delivery for Non‐Gastrointestinal Diseases by Oral Administration

Advanced Healthcare Materials, EarlyView.
Schematic illustration of the mechanism of targeted delivery of nanoparticles including 1) paracellular, 2) endolysosomal escape, 3) receptor mediated endocytosis, and 4) M cell mediated transport for non‐GI diseases by oral administration such as atherosclerosis, cancer, diabetes, and brain diseases. Abstract Oral drug delivery is a promising approach
Subarna Ray, Shehzahdi S. Moonshi, Hang Thu Ta   +2 more
wiley   +1 more source

Personalised Medicine in Cervical Cancer: Evaluating Therapy Resistance Through Multi-Model Approaches. [PDF]

Cancer Med
Meyer M, Eksteen C, de Sousa C, Chellan N, Van Aarde R, Bhaga M, Riedemann J, Botha MH, van der Merwe FH, Engelbrecht AM.   +9 more
europepmc   +1 more source

Recent Applications of Mesoporous Silica Nanoparticles in Gene Therapy

Advanced Healthcare Materials, EarlyView.
The review summarizes the synthesis of mesoporous silica nanoparticles (MSNs) with modifiable surface properties, functionalization strategies, mechanism of therapeutic payload release, and current applications in gene therapy, focusing on their capabilities in the targeted delivery of therapeutic nucleic acids, CRISPR‐Cas systems, and other genetic ...
Tamanna Binte Huq, Punnya Anil Kumar Jeeja, Sudip Kumar Dam, Sabya Sachi Das, Juan L. Vivero‐Escoto   +4 more
wiley   +1 more source

Synbiotic Supplementation Attenuates Doxorubicin-Induced Oxidative Stress and Inflammation in the Gut-Heart Axis of Chemotherapy-Treated Mice. [PDF]

Int J Mol Sci
Cheng CF, Nguyen TKN, Shen SC, Chen BY, Wu YB, Liang HJ, Wu CH.   +6 more
europepmc   +1 more source

Enhancing the Pharmacokinetics of Aptamers: Targeting AXL In Vivo Using a Bottlebrush Polymer‐Conjugated Aptamer

Advanced Healthcare Materials, EarlyView.
A phosphodiester‐backboned bottlebrush polymer (pacDNA) engineered for aptamer delivery is presented. This design enhances aptamer stability, plasma pharmacokinetics, and target engagement in vivo. In AXL‐driven cancer models, pacDNA inhibits AXL signaling and reduces tumor growth, highlighting the promise of precision polymer scaffolds in aptamer ...
Tingyu Sun, Jiachen Lin, Chenyang Xue, Yuyan Wang, Peiru Chen, Yun Wei, Guobin Xu, Anais Sidonia, Chris Nenopoulos, Hossam Tashkandi, Caroline Shen, Allison Wang, Alex Wang, Ke Zhang   +13 more
wiley   +1 more source