Results 291 to 300 of about 8,852,069 (358)

Phase‐Separation of YAP Mediates AJUBA Super Enhancer Activation to Promote Aberrant Mitosis in Breast Cancer

Advanced Science, EarlyView.
YAP undergoes phase separation to activate the AJUBA super‐enhancer, driving aberrant mitosis through spindle checkpoint dysregulation in breast cancer. This study uncovers a mechanistic link between YAP condensates, super‐enhancer activation, and aneuploidy formation.
Rui Zhang, Qingwen Huang, Zhuo Chen, Weijian Meng, Hongliang Dong, Zhihong Qi, Liang Liu, Jie Shen, Daxing Xie   +8 more
wiley   +1 more source

The inactivation of Cobalamin by nitrous oxide : application in experimental chemotherapy of leukemia

, 1987
Aloys C.M. Kroes
openalex   +1 more source

Pre‐Administration of Akkermansia Muciniphila Prevents the Development of Severe Acute Graft‐Versus‐Host Disease in Systemic Organs

Advanced Science, EarlyView.
Akkermansia muciniphila, a next‐generation probiotic, alleviates acute graft‐versus‐host disease (aGvHD) following allogeneic hematopoietic stem cell transplantation (HSCT) by providing protective effects across multiple organs. Pre‐colonization with A.
Jeong‐Eun Han, Dae‐Seong Lee, Su‐Won Jeong, Ji‐Hyun Yun, Seomin Kang, Seoyoung Jang, EunAh Lee, Ju Hye Baek, Che Ok Jeon, Jin‐Woo Bae   +9 more
wiley   +1 more source

IL1R2 Marks and Sorts a Spermatogonial Stem Cell Population Critical for Restoring Spermatogenesis Upon Interruption in Mammals

Advanced Science, EarlyView.
Spermatogonial stem cells (SSCs) provide critical support to spermatogenesis. Here, the author established Il1r2 as a sorting marker for SSCs, with which further insights into the SSC heterogeneity and dynamic features can be obtained. They also confirmed findings in both mouse and human, thus validating IL1R2 as the surface marker for isolating and ...
Pengyu Li, Zexuan Zhang, Zihan Xie, Cheng Jin, Zhipeng Wang, Changwei Yuan, Jun Zhu, Jielin Tang, Mengzhen Li, Dingfeng Zou, Xinyu Mang, Jun Liu, Dingyao Chen, Qi Geng, Yan Lu, Ning Zhang, Shiying Miao, Jing Peng, Kai Li, Wei Song   +19 more
wiley   +1 more source

TREM-1 inhibitor specificity and timing of treatment initiation can impact its therapeutic efficacy in cancer and inflammatory disease. [PDF]

Front Oncol
Sigalov AB.
europepmc   +1 more source

Resourcefulness training on cancer-related fatigue and fear of cancer recurrence in patients undergoing colorectal cancer chemotherapy: a quasi-experimental study. [PDF]

Front Public Health
Gao L, Zheng Y, Han N, Wu X, Yuan H.
europepmc   +1 more source

Comprehensive multi-omics analysis and experimental validation indicate that VPS35 is a promising biomarker for prognosis, immunotherapy, and chemotherapy in LIHC

Dan Wan, Yajie Qi, Yali Kang, Fanfan Liang, Qian Wang, Hailong Zhang, Wei Wei, X. X. Liang   +7 more
openalex   +1 more source

Re-defining standards of care in resectable head and neck squamous cell carcinoma-lessons from KEYNOTE-689 and NIVOPOSTOP. [PDF]

Oncologist
Mehra S, Yom SS, Burtness B.
europepmc   +1 more source

Conversion surgery vs. standard of care in pancreaTic cancer oligometastatic to the liver (SONAR: Surgery in Oligometastatic paNcreatic cAnceR) a randomized controlled trial. [PDF]

BMC Cancer
Guastella R, Perri G, Bassi D, Canitano N, Padoan V, Grandi S, Pellegrini R, Procaccio L, Bergamo F, Lonardi S, Carandina R, Gringeri E, Marchegiani G, Cillo U.   +13 more
europepmc   +1 more source