Results 311 to 320 of about 8,852,069 (358)
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Experimental Chemotherapy of Amebiasis
The American Journal of Tropical Medicine, 1947Summary (1) The pathogenesis of amebiasis is discussed. (2) Comparative amebacidal tests in vitro and in vivo have been made, utilizing improved appraisal technics. (3) The development of an essentially synthetic medium may lead to a more rational approach to the chemotherapy of this disease.
H H, ANDERSON +2 more
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Experimental chemotherapy of filariasis
Transactions of the Royal Society of Tropical Medicine and Hygiene, 1947General Summary This paper offers data obtained from a fairly large project on experimental chemotherapy of several filarial infections. The first work, performed in cotton rats which naturally harbour in filarial parasite known as Litomosoides carinii , showed definitely that this infection in this animal can be eradicated by the intensive ...
J T, CULBERTSON, H M, ROSE
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Experimental Preoperative Chemotherapy
1986Preoperative adjuvant chemotherapy in experimental tumors is not new; more than 25 years ago Brock (1959) described the advantage of preoperative chemotherapy in a rat tumor (Table 1). The results were quite impressive, especially if these tumors were more than 10 g at the time of treatment. Not all tumors show a similar response and for that reason it
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Experimental Cancer Chemotherapy
1954Publisher Summary Useful but not curative agents against cancer have been found. Steroids, carbamates, folic-acid analogs, nitrogen mustards, and related compounds are the most effective. While it can be anticipated that additional, active antifolic acids and nitrogen mustard-like compounds can be found, it is difficult to escape the impression that ...
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Experimental Chemotherapy of Neoplastic Diseases
Radiology, 1949It is intriguing to forecast the advances in cancer research that may be anticipated during the forthcoming decade. The exploration, by trained investigators with imagination, of such new fields as intermediary metabolism with the aid of radioactive and heavy isotopes, cytochemistry in conjunction with tissue culture, the isolation and identification ...
M B, SHIMKIN, H R, BIERMAN
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Chemotherapy of Experimental Clostridial Infections
Journal of Infectious Diseases, 1952Recent events have increased the interest in the treatment of clostridial infections. During World War II a considerable amount of information was accumulated on the efficacy of sulfonamides (McKee et al, 1943; Hac and Hubert, 1944; Hac, 1944a; Langley and Winkelstein, 1945; Ryan et al, 1946) and of penicillin (McKee et al, 1943; Hac, 1944b; Macfarlane,
J S, KISER +3 more
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Interstitial chemotherapy of experimental gliomas
Cancer Treatment Reviews, 1990Two new approaches of interstitial (intratumoral) chemotherapy of gliomas are presented. Using s.c.-transplanted rat gliomas (G616) the therapeutic activity of biologically degradable polylactide rods as carriers for methotrexate was investigated. Carrier-mediated intratumoral chemotherapy was superior both to a systemic treatment and an intratumoral ...
W J, Zeller +5 more
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Experimental Rabies Chemotherapy in Mice
American Journal of Veterinary Research, 1971SUMMARY Sixty-five chemical compounds classed according to biological activity were tested in mice to evaluate their therapeutic effect in postexposure rabies treatment. Mice inoculated with lethal doses of rabies virus were treated at the site of viral entry, systemically, or by “blocking” [i.e., injecting the treatment compound between the site of ...
J B, Enright +4 more
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Experimental Approaches to Antifungal Chemotherapy
1981Publisher Summary This chapter discusses the experimental approaches to antifungal chemotherapy. Fungal diseases in general occur in all parts of the world and affect all ages, though a number of particular species are restricted geographically in their incidence. It goes without saying that a systemic fungal infection will require systemic treatment.
J F, Ryley +3 more
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